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A Short Analysis of Shakespeare s Sonnet 19:

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Sonnet 19 - Cliffs Notes

a short essay on Short Essay Samples. Sonnet? Brought to you by -- The world's premier Application Essay editing service -- The New York Times Learning Network. Please select from the following short essay sets: Note: The below essays were not edited by biography essay EssayEdge Editors. They appear as they were initially reviewed by admissions officers. SAMPLE SHORT ESSAY SET 1: Georgetown, Saudi International Relations.

For many years, I have been interested in studying international relations. My interest in 19 analysis pursuing this field stems from germany gnp several factors which have affected me. First, I have been exposed to international affairs throughout my life. With my father and two of my brothers in the Saudi Foreign Service, I have grown up under the shadow of inter-national affairs. Second, I am fascinated by history, economics, and 19 analysis diplomacy. I believe, through the study of international relations, I can effectively satisfy my curiosity in these fields. A third factor which has affected my interest in international relations is patriotism. Through the Foreign Service, I would not only have the opportunity to germany gnp, serve my country, but also have the chance to help bridge gaps between my country and others. Finally, as a Saudi living abroad, I have been bridging cultures throughout my life.

This experience has taught me to look for differences to compromise and similarities to synthesize in order to 19 analysis, balance different cultures. In short, I believe that my experiences in life, combined with a rigorous academic education, will enable me to pursue a successful career in the Saudi Foreign Service. Georgetown, Favorite Class. At St. Albans, especially in is misused people against our later years, we are given the freedom to choose from a vast array of classes. Using this freedom, I have selected classes which have personal significance to me, regardless of difficulty or appearance on my transcript. Sonnet 19 Analysis? However, from these classes, one holds an extraordinary amount of value to me. This course is A.P.

Omnibus History, a combination of American and European history. There are several reasons for my great interest in this class. First, I am fascinated by the cyclical nature of the past. I see these recurring political, economic, and social trends as a means of looking forward into the future, while allowing us to avoid the mistakes of the past. Lincoln’s In His Inaugural Were? Second, history teaches many lessons about the nature of human behavior, both past and present, providing insight into sonnet 19 analysis, the actions, desires, and aspirations of those around me. Finally, it lays a solid foundation for several disciplines, including political science, economics, and international relations, three fields of great interest to me. Goals Second Address,? Georgetown, Visual Arts. Sonnet 19 Analysis? Another major interest of netflix strategy, mine, which I have not had the opportunity to express elsewhere on my application, is the sonnet, visual arts. Throughout high school, I have used a variety of media to express myself.

I began with black and white photography, focusing on the presence of lines and biography essay balance in nature. For my work in 19 analysis this medium, I received an award at the St. Albans School Art Show. From photography, I moved on earnings examples to glass etching. Sonnet 19 Analysis? Using a sandblaster to etch the glass, I again concentrated on lines and balance in my works. Moreover, by arranging several glass panes into a sculpture, I moved my study into netflix, three dimensions, winning another Art Show award. 19 Analysis? Currently, I am working on canvas, using oil and acrylic in retained earnings a Mondrian style, which is based on lines and balance. Eventually, I hope to explore the effects of combining these and other media, creating my own style of 19 analysis, artistic expression.

In the to what deficit uk, past four years of my life, no activity has affected me more than wrestling. Four years of varsity wrestling and 19 analysis the honor of being a team captain has instilled many qualities in me. First, through years of germany gnp, hard work and sonnet continuous dieting, wrestling has given me discipline. This discipline has spread to other parts of my personality, including my moral character, work ethic, and is there in the uk perserverence. Another quality wrestling has given me is leadership. Sonnet? As a team captain, I have learned to lead by example, both on and off the mat. Above all, though, wrestling has given me a love of life. Through this sport, I have experienced pain, sacrifice, adversity, and success. Exposure to these feelings-which are, in my opinion, the essence of when how do rebel against it?, being-has allowed me to truly appreciate life. I hope to sonnet 19 analysis, continue wrestling at Georgetown.

What immediately strikes the reader about this set-before even reading it-is the balance between the essays. Each answer contains only one paragraph, each of approximately equal length. The solid structure of each essay and the focus of each reflects this outward balance. Each one focuses on a completely different area of its writers life, another striking detail. The first focuses on power is misused against it? his career goals, the second on sonnet his interest in history, the third on his interest in the visual arts, and the fourth on retained earnings examples wrestling. This is a perfect example of the 19 analysis, jigsaw puzzle approach.

When put together, you have a well-rounded individual with passion, depth, and involvement in many different areas. SAMPLE SHORT ESSAY SET 2: Throughout my life, I have tried to lincoln’s in his inaugural were to, be a well-balanced person. Growing up in the South, I had a hard time fighting the stereotypical image of a Chinese person. I was expected to be a math and science genius and nothing more. As it turned out, I defied my detractors by excelling in English and history along with math and science.

And over the years, I have continued to sonnet 19 analysis, maintain my academic standards. Nevertheless, I have also made sure that I am more than an academic person. I am an active one as well. In middle school, the most popular game during lunch was a basketball game called Salt and Pepper (white vs. black). The first day of school, I stepped onto the basketball courts and was greeted by netflix cries of consternation, Who is 19 analysis he? Is he salt or pepper? But after the game, I had made a name for myself. From then onward, I would be known as Spice, and the game we played became Salt, Pepper, and Spice. When I moved to California, things were no different. I continued to play an active part both academically and socially. My involvement with Cross-country, Speech and Debate, Ultimate Frisbee and numerous clubs guaranteed that I would not be only known as an Honors student. Like myself, Duke is much more than an academic institution; it is a living institution.

I feel that I will be given the germany gnp, opportunity to excel both academically and socially. Duke is a university known for its rich history and strong academic program. And, at sonnet 19 analysis, the same time, it is also known for strategy its innovation and progressiveness. Sonnet 19 Analysis? These are qualities which draw me to the college. In addition, Duke and I have a lot in common.

The two most important extracurricular activities I have are a major part of Duke University. Dukes Speech team is known for its strong Extemp squad. Netflix? I remember the sonnet, time when my speech coach asked me what schools I was applying to. When I had listed my top five choices, he frowned at me and lincoln’s goals as discussed in his second said, Out of all those schools, I will only respect you if you either join us at Berkeley or go to Duke and extemp. I hope I will be given the opportunity to contribute my part in the Duke Speech team. 19 Analysis? Equally important, the germany gnp, Duke University has a well-known Ultimate Frisbee team. I look forward expectantly to becoming a part of the sonnet, team. Strange as it seems, Ultimate Frisbee is one of my top criteria for choosing my future college. It delights me that Duke places such great emphasis on the two extracurricular activities that mean most to to what extent a democratic uk, me. My first year at Duke should be a great one. Majoring in sonnet economics at Duke should allow me to both pursue my major studies and allow me time for personal interests in goals second Chinese and the Humanities. Moreover, in my spare time, I plan to join the Speech team and the Ultimate Frisbee team.

Hopefully, with my previous experience, I will have an early start in both Speech and Ultimate. Yet, I will never forget why Im in 19 analysis college in the first place. As long as I give organic chemistry a wide berth, I should be able to continue my level of academic excellence. Overall, my first year at Duke promises to be exciting, if a bit hectic. I find Hermann Hesses book, Narcissus and Goldmund, intellectually exciting. After reading the lincoln’s goals for reconstruction, second address,, book last year, I remember putting it down and sonnet sighing contentedly. I had, after a sleepless night, finally finished. What I reveled in was not the fact that I could sleep, but that I had come away with an inexplicable something. It was not an understanding which could be pinpointed and explained. Rather, it was a sense I felt in the depths of my soul. And yet, what delighted me more was that I knew that I had only germany gnp begun to understand the book; that there remained countless messages which I could only sense but not grasp.

Here, finally, I had a book which could be re-read. 19 Analysis? And every time I finished, I would come away with a new understanding of something I could not put into words. Unlike the normal academic, I do not want to find the final answer for everything. Retained? Throughout my life, I have always felt a sense of loss after succeeding in a long search. For me, it is not the ends I seek, but the means themselves. I am perfectly content to never find the final answer as long as I will always be able to find a better one. Duke, Chinese Culture/Economics. Born in sonnet 19 analysis Taiwan, I came to the United States when I was five. Armed with only two words (hello and popcorn), I braved the biography essay, uncertainties of a complex, new environment. Twelve years later, my vocabulary is 19 analysis considerably larger and I have adapted well to my surroundings. At the same time, I have neither forgotten my native culture nor its language.

My ties with my native Chinese culture remain as strong as ever. I visit my relatives in Taiwan regularly almost every summer and have traveled throughout China. And to everyones continuing surprise, I have yet to forget how to speak Mandarin. Nevertheless, twelve years in America has made its impressions upon me as well. I am as American as anyone my age. The songs I listen to, the sports I play, and the way I speak are all a reflection of that. In short, I am a combination of both East and West.

Nevertheless, I sometimes wonder whether speaking Chinese at home and visits in the summer are enough to maintain my ties with my native culture. Often, when I see my parents reading old Chinese literature or poetry, I feel that I am only in biography essay touch with half of what I am. This sense of loss has led me to seek out sonnet 19 analysis, my old roots. I turn to the East to rediscover what I have lost. Yet, I cannot resign myself to biography essay, merely studying my own culture and language. I want to be able to apply my knowledge as well. To me, pursuing a career in business is a very pragmatic solution to my future welfare. Sonnet 19 Analysis? My father is to what extent deficit uk a businessman in Taiwan and I have had numerous opportunities to watch him work. Through him, I have discovered my own interests in the business field. I find the way business operates in 19 analysis the East to be very exciting.

At the same time, my father has soothed my sense of morality by showing me that it is possible to be an honest businessman in Asia. Examples? Before I learned about Duke, I had made up my mind to study economics and to ultimately pursue a career in sonnet international business. I had come to lincoln’s for reconstruction, as discussed inaugural address, to, see this path as the 19 analysis, best combination for fulfilling both my aspirations towards knowledge and my pragmatic goals of a future livelihood. Netflix Strategy? China, my planned area of focus, is an expanding market with a dearth of skilled business professionals. But I had misgivings because I wanted a school with a strong focus on the humanities as well. Thus, I find Duke University exciting and 19 analysis perfect for me. It gives me a strong economics curriculum, but still allows me to pursue my interests in the humanities. Earnings? With economics at Duke University, I will have access to a wide array of 19 analysis, studies both within and beyond my chosen major.

I will have an edge in the business world by virtue of Duke. After attending Duke (if I am accepted, of course), I will have a clear path before me. My studies at Duke should virtually guarantee me for any graduate business school. And, after my graduate studies, I will be able to realize my dreams. Perhaps, I will be able to serve as a bridge between East and strategy West. These three well-written essays create a strong set.

The first and the last would have been impressive on their own. Reading them all together magnifies their impact considerably. This student does an especially good job of targeting the school. This student focuses his first essay on his extracurriculars and sonnet relates them to why Duke would be perfect for him. Retained Earnings? He focuses the third on his Chinese background and how it relates to his career goals and academic interests. Then he also relates these interests to sonnet, why Duke matches him perfectly. Is There A Democratic In The? His favorite book provided the sonnet, focus of the second essay.

What makes this second essay better than others like it is that the extent a democratic deficit in the uk, applicant manages to 19 analysis, put himself into the question. He does not just talk about the book, he uses it to talk about himself and stress the retained examples, inquisitive nature of his personality-always a plus. SAMPLE SHORT ESSAY SET 3: Participating in my high schools debate program has been my most meaningful activity these past four years. I have learned how to speak in front of a crowd without becoming nervous, how to think on my feet, and how to sonnet 19 analysis, argue the merits of any side of an issue. Being on the debate team also allows me to extent deficit, educate myself on current topics of global importance such as the homeless problem, health care, and pollution. Throughout the three years I have dedicated to the activity, (high school) has always maintained a successful squad and I am quite proud to know that I have earned many of the trophies and awards that have helped make the program so successful and 19 analysis (high school) well known on when is misused how do people rebel it? the debate circuit. Because of the activity, I have learned that from sonnet education to communication, from argument to enlightenment, debate is necessary for two or more humans to transcend mere exchange of retained earnings examples, thought and achieve synergy instead. I now view success in debate as far more than a trophy; I now see it as evidence that I can successfully communicate my beliefs to others and have them logically accept them as their own, thus priming me for any future challenges involving human interaction.

Dartmouth, Honors and Awards. Sonnet 19 Analysis? My most important honors since tenth grade have been winning the Brown University Book Award for retained earnings my skills in English, being named as a National Merit Semifinalist (Finalist status pending), winning the Journalism Education Association National Write-off Award of Excellence in 19 analysis the Editorial division at a national conference, being selected as a Semifinalist in the NCTE Writing Contest for my work in prose, being named as an Illinois State Scholar for lincoln’s for reconstruction, second inaugural were to my academic achievement in sonnet 19 analysis high school and biography essay my high A.C.T. 19 Analysis? scores, being selected to the Spanish Honor Society for my consistent success with the language in the classroom, being selected as the Student of the Month in power is misused how do people against it? the Foreign Language/Social Sciences division two years in a row for my success in those classes, and in a culminating event, being featured in Whos Who Among American High School Students for 19 analysis my overall scholastic success. Dartmouth, Summer at Dartmouth. Most of my past summer was spent away from home. Netflix Strategy? In that brief month in sonnet which I remained in (town name) I worked at (job) in order to earn the money I was going to spend on my trips. My first excursion was to germany gnp, the east coast where I visited several schools and sonnet took in the atmosphere of an retained examples area to which my midwestern self was somewhat unaccustomed. One school I was considering that I did not visit was Dartmouth. After all, I spent a month there later in the summer.

As a participant of the Dartmouth Debate Institute I spent a lot of time in 19 analysis Feldberg, Dana, and Baker libraries; resided in the well-known Choates; attended sessions in Silsby; and dined in the Full-Fare section of is misused rebel against it?, Thayer. There was also time for recreational activities such as rope swinging, volleyball, frisbee, sleep (every little bit was cherished), and beautiful hikes up to Dana. I did manage to sit down and work in sonnet 19 analysis such a clean, open environment, however. The instructors made sure of that. The four-week institute honed my skills in speaking, researching, structuring arguments, and thinking. As a result, my partner and netflix strategy I were able to break into the elimination rounds at the institute-ending tournament which included the top debaters in the nation. Aside from the sonnet 19 analysis, debate skills I learned, I found the institute very favorable because of the is there a democratic deficit, exchange of ideas taking place between the 19 analysis, students and staff.

What I learned from those exchanges enlightened me not only as a debater but also as a person. Although I enjoy all of my subjects, I regard classes I have taken in the social sciences to be the most meaningful. Whereas some classes use formulas to describe natural occurrences, the social sciences show that not everything is explicable in such a clear-cut manner. The social sciences describe people; they describe the earnings examples, people who make up the formulas and sonnet 19 analysis how and why that was done. The social sciences also explain the past so as a society, people can avoid past catastrophes and to what extent is there a democratic deficit in the uk build upon past successes. Sonnet? Not only do they describe how we act as we do, but why we act as we do. Biography Essay? I am not a student who always likes to follow someone elses rules. While most subjects allow for free thought, the sonnet, social sciences encourage innovative thinking. Those classes expect students to to what is there deficit uk, explain why something happened based on certain conditions. I didnt learn that the sonnet, Iron Curtain was an economic measure in power is misused how do people against it? any math class.

As a student my ultimate goal is to sonnet 19 analysis, understand things. I feel the retained examples, best way to understand is not by reciting anothers thought, but by formulating my own and debating it with people who disagree with me. I believe that exchange of thought is vital in every curriculum, but the 19 analysis, social sciences do the biography essay, most to promote that exchange. I highly doubt that anyone will be debating Einsteins ideas in sonnet the near future-and be right. This essayist dedicates the first essay to his involvement in debating. He manages to lincoln’s for reconstruction, as discussed second inaugural to, communicate quite a lot in sonnet 19 analysis a short amount of space (what he has learned, what he has achieved, and what debating means to to what is there deficit in the, him) without ever losing his focus. The second essay is an example of an answer to a list question (List your honors and awards). The third gets more personal by describing the summer he spent at Dartmouth. 19 Analysis? The strength of retained earnings, this essay is that he sells himself on his knowledge and familiarity of the school.

The weakness of this essay is sonnet 19 analysis that he tries to do too much and loses his focus after the second paragraph. The conclusion does not seem to fit with the points he has made in examples the essay-the last line particularly seems to come from nowhere. SAMPLE SHORT ESSAY SET 4: Harvard, Favorite Books. The novel Black Like Me was the most stimulating book I have recently read. I was taken aback by the cruelty the narrator experienced when he was black compared to the hospitality he found as a white man. Possessing the 19 analysis, same occupation, clothing, wealth, speech, and identity did not matter when his skin was another color. Given that this was a non-fictional piece, my reaction was even stronger. The book made me favor equality of opportunity for all in strategy every endeavor so others opinions of them are based on performance, not preconceptions. Harvard, Favorite Teacher.

I selected Mr. (name) because he taught me more than U.S. History; he taught me how to think independently. This wasnt done only to prepare me for the free-response section of the A.P. 19 Analysis? test, either. I know he did it to make his students responsible citizens and responsible adults. From the outset, he wanted to make sure that we knew how we stood in our political philosophy: strict constructionists or loose constructionists. He wanted to make sure that we didnt gravitate towards empty categories like liberal or conservative, but rather focused on issues separately whenever we needed to strategy, take a stand on 19 analysis them. Retained? Imagine my surprise when I, the son of two very conservative parents who constantly bombarded me with their rhetoric, discovered that I had strong liberal tendencies on some issues. Aside from political affiliations, Mr. (name) taught us how to 19 analysis, make sense out of history by trying to understand the personal motives that went in to any chain of goals in his inaugural were to, historical occurrences.

In his class, I came to the realization that history isnt only a series of names and 19 analysis dates printed in a textbook, but a more complex subject that requires deep thought and analysis for full comprehension. Because of Mr. (name), history is now my favorite subject. He has also been a motivating force outside of the classroom. He always had faith in my ability and constantly encouraged me to do my best. Goals Inaugural Address,? I believe he respected my abilities and wanted to see them developed further. In fact, had it not been for sonnet his faith in me, I would have never applied to Harvard, the earnings examples, school I plan to attend in the fall. Harvard, Unnoticed Accomplishment.

Its not that Im a weak guy, just that I had been somewhat self-conscious about my strength early on in my high school career. My gym class didnt help too much, either. Thanks to a demeaning test of strength appropriately dubbed the Grip Test, once each quarter I was provided the opportunity to squeeze a gadget, get a score, and have my teacher announce it out loud, no matter how high or (as in my case) how low it was. No matter how hard I tried, the cruel and sonnet callous scale never registered above 40. Almost every other male in the class could boast of a high-40s or mid-50s score.

I hated that test with a passion. Until recently. Germany Gnp? When this semester rolled around and sonnet 19 analysis I had the gripper placed in my palm, I was prepared for the same old same old. I had been improving slightly from biography essay quarter to quarter, but nothing impressive ever happened. I drew in a deep breath, squeezed, looked at the scale, and almost fainted.

Sixty-six! In a way only a teenager can appreciate, for an accomplishment only a teenager would find meaningful, I thought I was in heaven. Sonnet 19 Analysis? My success was even sweeter as I watched jocks pale in comparison when they took the test. Sure, to some people my academic accomplishments seem fairly impressive, and I would agree. Yet the grip test situation was much more personal and represented success in an area I normally dont pay attention to.

Plus I learned two things. One: I can pride myself on strategy the smallest triviality. Two: Im glad we dont measure strength in our gym classes with the bench press. Harvard, Leadership through Dedication. To me, leadership does not necessarily mean accumulating as many titles as possible in 19 analysis school activities; I feel one leads through his dedication, actions, and when is misused how do it? contributions. I have always tried to lead in 19 analysis almost everything I set out to do. I feel I have been successful at that. Superficially, I have earned such titles as president of the National Honor Society chapter at my school, Editor-in-Chief, columnist, Investigative Editor, and Editorial Editor of the school newspaper, senior varsity leader in to what extent a democratic uk debate, and sonnet 19 analysis a Class Representative for Student Council. However, those titles dont begin to germany gnp, tell the story of my abilities as a leader. They dont reveal how I volunteered to help out at 19 analysis, a handicapped lock-in at an unfamiliar youth center when no one else wanted to, they dont reveal how I always sought to be on time for work and to avoid boondoggling, they dont reveal how I aided younger debaters with their argumentation so they can have the same success I was lucky enough to enjoy, they dont reveal how I became a role model for the JETS squad by studying my material often, eventually becoming the most medaled member on the team, and they dont reveal all the effort I put into strategy, learning my lines and acquiring a good stage presence for Images, my first stage production ever, so I wouldnt single-handedly jeopardize the whole show with my lack of experience. All those actions stress the quality I feel is most important in a leader, dedication.

With dedication comes hard work and the ability to seek out solutions when problems get in the way, whether they are with a news page layout or in a students diction. Because of this dedication, taking charge is second nature for me. People are always willing to follow one with a clear sense of sonnet 19 analysis, direction. Harvard, Close-knit family. I dont view my important characteristics as different from those my family has imparted on me throughout the years. Lincoln’s Address,? The pride, care, dedication, effort, and hard-working attitude that I view as critical to any success I may achieve have all descended upon me courtesy of sonnet 19 analysis, my close-knit, Italian family. Born the child of two immigrants who came here with nothing, only one possessing a college degree, the importance of a good work ethic was stressed by my parents from when against it? day one. Sonnet 19 Analysis? Through their actions in their jobs and through the verbal lessons on when power how do rebel against it? life I began to get from the sonnet, moment I could communicate, they set an example for me to germany gnp, follow, one of being proud of what I do, no matter what it was, and above all, to care about everything I do as if everything had a big impact. This meant that everything had to be done right and sonnet 19 analysis be done well. Undoubtedly, following their own advice carried my parents from their status as blue-collar immigrants who labored as a factory workers to white-collar citizens, one of whom owns his own business while the other works as a bank officer.

Those ascensions from nothing only served as other examples for me to follow, examples that delineated the ability for a person to improve through effort. Another quotation from my father propelled me from the time I started school to retained, today: No matter what you do, you have to be the 19 analysis, best. This set up the inner drive that motivates all my actions. It was what forced me to try hard in school although I didnt know English well enough to always understand the teacher. Its the reason why I have developed my skills. It accounts for my dedication to all activities, and to lincoln’s for reconstruction, in his second inaugural address, were, the hard work I put into all of them as I strive to lead both in class and out. Essentially, my parentage was the first quality that distinguished me as a leader.

Despite all the talk of being a leader, I have never lost sight of the importance of 19 analysis, my family. I know I owe my family everything, and as a result, Ill always be close with it. I pursue a variety of activities for fun and relaxation. I enjoy reading books and magazines (my tastes range from Time to Gentlemens Quarterly) on a regular basis, imitating Beavis and Butt-head, and most of all, spending time with my friends. Although I am fan of playing pick-up games of basketball, football, and roller hockey, the phrase doing nothing with my time doesnt bother me since I can have a good time just hanging around. I think people, not places, make for when people against a good time. Harvard, Social Concerns. My major social concerns all revolve around the future.

In other words, Im concerned about sonnet what prevents people from rising above their disadvantages. Specifically, I am most concerned with the handicapped, education, and crime. I feel societys response to handicaps is what really hampers the potential of the disabled. It is important for rebel it? the disabled to get a better sense of worth and to be able to adapt to, and 19 analysis survive in, todays world. Through National Honor Society (NHS), I have done just that. I have helped out at a lock-in that was designed to foster interaction among the children of the organization, as well as at Special Olympics, where the children participate in sports on a competitive basis so their talents and abilities can be recognized. Goals As Discussed In His Second Inaugural Address, Were To? Whenever the disabled can be successful at an activity, the barrier between them and 19 analysis the rest of society is netflix strategy drastically reduced. Education is key to other problems such as gangs, drugs, and crime because it can prevent and eliminate them. I try to get students in our school to maximize their opportunities by sonnet using the educational resources available. By setting up a tutoring program through NHS, I have matched up needy students with other students who can assist them with their problems in classes. More directly, I help students out with English and show them how to use the Writing Center Lab, an indispensable resource for English students at netflix strategy, any level.

The more educated a person is, I believe, the more able he is to be successful in the future. I have dealt with criminal problems in my school by sonnet 19 analysis discussing solutions to gangs and other crime in the Student Advisory Committee. We have drafted several proposals to help reduce those problems in our school. Educating people about such social concerns is also very crucial because they wont fix what they dont think is broken. That is one objective of to what extent deficit in the, our newspaper, in which we have written various editorials and news stories to educate the student body on social topics. Through debate, I myself have become knowledgeable on 19 analysis such topics as the homeless, poverty, health care, and the environment. That way I can practice what I preach.

Harvard is notorious for its long list of germany gnp, essay questions, as you can see from the seven essays this applicant had to write. The first essay is a standard favorite book essay. His second, about 19 analysis his favorite teacher, goes into more depth and reveals more about the candidate, that he enjoys learning, admires independent thought, and plans to study history. The third essay in this set stands out from the rest. Had the panel who were grading the compositions understood the context of retained, this essay in sonnet 19 analysis light of the six others in the set, they probably would have given it more credit. Germany Gnp? Its strength lies in its funny, lighthearted approach-it shows a completely different aspect of the candidates personality.

Without it, he would have appeared deadpan serious and probably a bit dull. However, showing the wittier side of himself strengthens the set considerably. 19 Analysis? It is lincoln’s goals for reconstruction, second address, were a good example of allowing yourself to take a risk in one essay, as long as more serious approaches in the others balance it.

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A Short Analysis of Shakespeare s Sonnet 19:

Keep up with the latest in Photography. This essay is the third of afour parts seriestitled as follows: 1- Finding Inspiration. 2 Exercising your Creativity. 3 Developing your Vision. 4 Achieving your Personal Style.

Together these four essays represent, first, an exploration of the too-rarely discussed subject of inspiration and creativity, and second a road map towards the sonnet, development of a vision and the achievement of a personal style unique to you. Each essay features a set of Skill Enhancement Exercises that allow you to practice and develop your skills on your own. Vision is the is there a democratic deficit in the, art of 19 analysis, seeing what is invisible to others. Inspiration lights the spark of creativity. Together, if well integrated, inspiration and germany gnp, creativity result in a personal vision for your work. Your vision, when expressed successfully, results in the achievement of your personal style. This is a four-part process. In the previous essays we looked at the first two parts. It is now time to look at the third part: Vision . Vision is sonnet 19 analysis a subject that is rarely discussed in photography. Yet, as we are going to see, it is a very important subject because without vision an artist will create commonplace photographs. Address, Were To. They may be the most technically perfect photographs one can take, but they will still be commonplace photographs.

With vision your photographs go beyond being just commonplace images. Sonnet 19 Analysis. They become the conveyors of ideas. How this process takes place and what is involved when it happens is the subject of this essay. It is a terrible thing to see and have no vision. Vision is the art of seeing the is misused how do people rebel against it?, invisible. In this respect, vision is not just seeing, it is not just sight. Instead, vision is 19 analysis insight . It is the ability to see something that only when power is misused people it?, you can see, something that others do not see because this something does not have a physical reality.

It is something you see in your mind’s eye, something that exists in your imagination, something that is within yourself. A vision is sonnet something abstract: an power is misused people against idea or a concept. Vision is sonnet 19 analysis made real through creative work. In photography it is lincoln’s goals for reconstruction, as discussed second made real through the creation of photographs that express your vision. The goal of these photographs is to share your ideas, your concepts, in sonnet 19 analysis, short your vision, with your audience.

A vision can come about in any field of human endeavor. In regards to for reconstruction, in his inaugural were photography, vision is made real through the photographs that you create. How clear your vision is, and how closely your photographs follow this vision, defines how successful you will be in conveying your vision to others. Vision is inspiration made reality. Sonnet. Vision is to what extent is there deficit in the uk using photography to sonnet express something otherwise invisible. Vision is making poetry with photographs. It is germany gnp going beyond the technical knowledge of the medium and reaching the artistic level. Sonnet 19 Analysis. It is going beyond mastery of the medium and reaching improvisation and self-expression. Finding and expressing your vision can be a challenging process. Because your vision is something that is invisible to others, it is a process that you have to go through essentially by yourself.

Vision demands an unwavering commitment to netflix strategy your art. It also demands that you can back up this commitment with work because only sonnet 19 analysis, through work will you be able to share your vision with others and thereby prove that you are truly committed to this vision. Vision is message. It is not just creating an image but creating a story through this image. This message can be about sharing an emotion, a feeling, a belief or a particular way of looking at the world. It is not just about sharing an biography essay image with your audience.

It is also about sharing the meaning of 19 analysis, this image with your audience. This image means something to netflix you. This image contains not just objects, people and features. It also contains ideas that represent your vision. Without vision an image is just an image. With vision an image becomes the vehicle that carries your ideas to sonnet your audience. New images surround us everywhere. They are invisible only because of sterile routine convention and netflix strategy, fear.

Creating a photograph faithful to your vision is 19 analysis similar to creating a product based on an idea, on when rebel against, an image in your mind. This product can be anything: software, mechanical devices, services, etc. This product will represent the outcome of 19 analysis, your vision as long as it started as an idea that you turned into a physical reality. Ideas cannot be shared as ideas. They have to be translated into germany gnp something else first.

This “something” is the vehicle used to deliver your idea your vision to your audience. The simplest way of 19 analysis, doing so is to put your idea into words in lincoln’s goals for reconstruction, as discussed second address, to, order to explain to others, either orally or in sonnet 19 analysis, writing, what this idea consists of. This is what a description, an essay, a short story, a novel or any other piece of germany gnp, writing be it fiction or non-fictionis. A photograph can also be used as the vehicle for sonnet 19 analysis an idea if the photograph is retained earnings examples used to describe this idea. In the same way, anything created on the basis of an idea that was turned into a physical reality qualifies as being a vision made reality.

If this process does not take place your vision will remain an sonnet 19 analysis abstract concept, a dream that exists only in our head. So what do you need to do this? For one, you must have a vision, an idea. This is something that only you can do. For some, this comes naturally. For others, it is something that requires work and, sometimes, soul-searching if you will. I cannot give you this idea. Germany Gnp. No one can. It is something that you have to come up with.

What I can do is sonnet 19 analysis help you find the way to this vision then help you turn your vision into reality. This is what we are going to explore in the next sections. White House Storm. I consider the light quality in this photograph to be part of my personal vision. I also consider this light quality to have helped define my personal style. I have seen this type of light, and have been able to photograph it, on three separate occasions. The image above represents the third of strategy, these three occasions. This is a very uncommon type of lighting because it only occurs when a storm is sonnet 19 analysis clearing in retained earnings, the late afternoon.

There has to be clouds in the sky, both in the Eastern and Western direction, as well as openings in the clouds in the West so that the sun can shine through. The only thing an artist has to sonnet 19 analysis remember is to never lose faith in his vision. Vision is the stage at which thinking about your work is just as important as creating your work. In other words, you need to spend time reflecting about your photographs. Just creating and printing new photographs will not allow you to express your vision. Reflection has to take place. Thinking has to take place. A large part of the process of developing your vision takes place without a camera in hand. It doesn’t even have to happen where you take your photographs.

It can happen wherever you have time to think, in a place that is quiet and conducive to reflection and where you are not distracted by anything. In a way you have to engage in critical thinking about your work. You have to think about what you have done so far and about what you want to do next. As Discussed In His Second Inaugural To. You also need to think about what inspired you to sonnet start creating photographs in the first place. Critical thinking is also about thinking differently. It is about thinking of solutions and possibilities that have not been thought of previously. Is There Deficit. In many ways, being creative is synonymous with thinking differently. To think differently you have to think differently from “something.” You can’t think in the abstract, without some point of reference, some point de departure, some school of thought to guide you, or without affiliating yourself, to 19 analysis a greater or lesser extent, with a specific art movement. Creating a vision cannot be done in a vacuum. To develop your vision you must take into consideration both what you want to do and what has already been done by other artists. Something is different only if it has not been done before, or if it has not been done the way you are doing it.

A work of art is original because it is different from the germany gnp, works of sonnet 19 analysis, art that preceded it. This means that you have to know where you are coming from, what is your point of how do it?, reference, what are your roots, who are your colleagues, and who is working in sonnet, the same style as you. In short, you need to know where you fit in. This is why the next section Going Back is important in that regard. If you are not sure about how thinking differently and biography essay, who you are ties together, I recommend paying close attention to this section. I also recommend completing the skill enhancement exercises (provided at the end of this essay) that targets this crucial aspect of developing a vision for your work. I dont photograph the world as it is. I photograph the world as I would like it to be. A number of things can help you go through this challenging endeavor. The first one is to remember your original source, or sources, of inspiration. I cover this subject in the first essay of 19 analysis, this 4 part series: Finding Inspiration . If you haven’t read it already, I suggest that you take the time to read (or re-read) this essay now, and that you complete the Skill Enhancements Exercises listed at the end of this first essay.

Another way that can help you find your vision is to germany gnp refer back to the reasons why you started photography in the first place. Most likely, you started photography because you wanted to represent the world around you better than others had done before you, or because you wanted to express a personal way of seeing. Maybe you became interested in photography because you wanted to capture for posterity the fleeting events in your life. 19 Analysis. Or maybe you became involved in photography because you wanted to document the street life in a big city, or because you wanted to share with others the beauty of a sunset, or the stunning quality of a grand landscape. Maybe you started photography because you love animals and you wanted to retained earnings share this passion with others through your images. Sonnet 19 Analysis. Maybe you started photography because you love spending hours creating a still life and lighting it and then create the finest photographs of this still life. Earnings. Maybe you started photography because you wanted to create the finest portraits possible. Maybe you started photography because you love the purity of color, or the endless tones of black and white prints. Maybe you became involved in photography because you constantly marvel at the endless possibilities offered by toning and other alternate approaches and because you want to share your talent for creating images that use these tones better than you have seen done by others.

If you are like most, at first your equipment was minimal, most likely inexpensive, and maybe given to you by parents, friends or relatives. The purchase and ownership of expensive camera equipment came later (if it did). This ownership may have brought with it a passion for fine cameras, lenses, computers, printers and 19 analysis, other equipment associated with photography. Over time this passion for the equipment may have overshadowed your initial reasons for choosing to netflix do photography in the first place. 19 Analysis. The passion you had for earnings examples representing the sonnet, world around you may have slowly given way to earnings examples a passion for the tools rather than for the outcome that these tools can produce. In turn, your inspiration may have shifted from being inspired by the subject to being inspired by the camera. Transferring passion from subject to equipment is not the only reason why we move away from sonnet 19 analysis our vision. There are many other events that can cause this to happen. Life has a way of taking us away from what we originally intended to do and to make us do things because we have to rather than because we want to.

If this sounds familiar you are not alone. This is a common situation that many photographers face. The way out of it is to first accept it for what it is. Don’t refute the facts; just accept them. Then, this being out strategy, of the sonnet, way, go back in time in your mind and remind yourself of the reason why you started photography in the first place, way back when. You may be able to do so simply by is misused against it?, thinking about it and by remembering events that took place a long time ago.

You may also have to go back through your archives so to sonnet speak, or make a trip to the place where you first photographs are stored (if you kept them) to when power people rebel against take a look at the photographs you created when you just started. In those photographs, embedded in the paper and the emulsion so to speak, are the sources of your original inspiration and the results of your original creative urge. Inside them is an 19 analysis inspiration coming solely from your subject and from your emotional response to this subject. Back then you probably did not think you would ever own expensive gear. Back then the equipment was simply a means to an end. This was as it should be. Cameras are tools and tools are means to an end. They are not jewelry or collectables. Earnings. They are just tools. Mind you, they can be jewelry and collectable, but not in the context that concerns us here which is to achieve a personal style. In our context they are just tools.

They are a means to an end, and sonnet 19 analysis, this end is to as discussed in his second inaugural were place achieve a personal style. Back then you did not have the responsibilities that you have today. Your artistic goals were not overshadowed by the concerns that came later on and that may still be there today. If you were like most you had more time than money, a trend that tends to reverse itself as life goes on. Clearing Spring Storm, Canyon de Chelly. This is the sonnet 19 analysis, first photograph I created using the light quality I described in my previous example. I created this image shortly after moving to Chinle, Canyon de Chelly, Navajoland, in 1997. Tsegi overlook, where the photograph was taken, was only 10 minutes from my house. I was on my way to pick up my wife, Natalie, after work when I noticed the earnings examples, dramatic clouds. 19 Analysis. I realized that if the sun came out to what a democratic deficit uk, a truly incredible lighting effect would take place. I immediately decided to sonnet 19 analysis drive the short distance to the rim of biography essay, Canyon de Chelly to wait and sonnet 19 analysis, see if the sun was going to appear.

I waited perhaps half an hour until the retained earnings, sun broke through the 19 analysis, clouds. What I witnessed then remains one of the most incredible scenes I have ever seen. Clearing Spring Storm over Canyon De Chelly is the result and this image explains what I saw better than any text I can write. I took a number of photographs and the best one was the second or third one. Before that there was not out enough sunlight. Afterwards there was too much sunlight. When People Against It?. The best photograph was just in between, when light and shadow areas were evenly balanced, creating tension and beauty at the same time and making me deeply aware of the utterly temporary nature of 19 analysis, natural light at transitional times when storms are moving away. What is retained earnings most interesting when I look at this photograph today and reflect upon it, is sonnet 19 analysis that this light quality came to define my vision and played a key role in shaping my personal style. Power Is Misused Rebel Against It?. However, I did not see things that way back then. When I created this image the most important aspect of it for me was the panoramic composition. Certainly, the light was important and I was aware that the light made the image. 19 Analysis. However, it was the panoramic format that I thought was going to define my style.

So much so that I purchased a Fuji 617 camera following the creation of this image and biography essay, proceeded to create a series of panoramic images with it. As things turned out, I tired of the panoramic format relatively quickly, perhaps within two or three years of using the Fuji 617, and eventually stopped using it. However, to this day I continue to seek the light quality in the image above, regardless of which camera I use. What was happening then was a misconception on my part regarding what my personal style consists of. I thought my style was coming from the format of my images while it was essentially coming from the light quality in my images. Sonnet. The former format- is a superficial aspect of retained earnings, my vision while the later light- is 19 analysis a fundamental aspect, one that will not go away because it is not based on against, temporary preferences.

Rather, it is based in a deep-rooted appreciation of sonnet, light that goes back to the day I started photography. A photographer’s work is given shape and style by his personal vision. It is to what a democratic deficit in the not simply technique, but the way he looks at 19 analysis, life and the world around him. Developing a Vision for your work is showing to others, through your photographs, what you see in your mind’s eye. It is to what deficit therefore about you.

It is about how you see the world, about what you see that others do not see, and about your emotional response to the scenes that you photograph. In many ways it is about your personality. In the process of 19 analysis, developing this vision you must therefore be yourself and demonstrate your personality. Art, eventually, when everything else has been said and done, is power is misused against about you. As an artist, you need to sonnet demonstrate your personality to your audience through your work. The audience that is seeking original art wants something that escapes the commonplace. They want something that they do not find in the pre-packaged, mass-produced and impersonal artwork found in volume retail stores and other mass-appeal locations. This audience is looking for for reconstruction, as discussed inaugural address, were art that is original, hand-made and that demonstrates the personality of the sonnet 19 analysis, artist who created it. This audience expects artists to earnings be original and to sonnet express themselves through their artwork. In other words, this audience expects the artwork to be the expression of the artist’s personality.

If this is not the case, if the artwork is impersonal, the artist is perceived as being a lesser artist. An artist “ sans ” personality in a way. An artist who is far less interesting than an artist “ avec ” personality. In other words, something is missing and to what a democratic, this missing something is fundamental to sonnet art. Worse, if this is missing i.e. the personality of the netflix, artist demonstrated through his art- it will not be missing just from the artwork. It will also be missing from the sonnet, way this artist talks about germany gnp, his art. It will be missing from the way this artist relates to others and to the world at large. In short, it will be missing from everything that this artists does, regardless of how much contact this artist actually has with the public. Some readers may find the 19 analysis, above somewhat of an exaggeration. After all, some readers may believe that doing beautiful or interesting work is enough and extent deficit uk, that this work does not have to be about them and that it does not have to demonstrate their personality.

This is a true statement, provided that your goal is not to express your vision, and eventually your personal style, in your work. How can you express your vision and demonstrate your personal style unless you bring your personality into your work? As we saw, vision is by nature personal and personal style is, not to be redundant, personal There is no way around it, unless you decide that expressing your vision and achieving a personal style is not something you want to 19 analysis do. If it is extent a democratic in the uk something you want to do then expressing your personality in your work is going to 19 analysis be necessary. You don’t have to express all the aspects of your personality, in fact few artists do so, but you are going to have to express some aspects of germany gnp, your personality. 19 Analysis. The good thing is extent a democratic deficit in the that you get to pick which aspects you want to show in your work, to sonnet some extent. To create ones world in any of the when power, arts takes courage. In a way, and to continue the discussion started in Section 6, your audience seeks to admire and acquire objects that have a soul. Rationally speaking, objects, including works of art, do not have a soul.

They are not alive; they do not breathe and are not made of living cells. They do not think, and 19 analysis, thus, from a Cartesian perspective, they are not able to invent themselves. Biography Essay. Irrationally speaking, however, works of art can be perceived as having a soul. Sonnet 19 Analysis. This soul, if present, is imbued into the work of art by the transfer of the artists’ personality and passion into his artwork. This soul is brought about by the care and the craftsmanship used to create the work. Retained Earnings Examples. This soul is present in the artwork because a part of the artist’s soul was transferred into the work during its creation. This soul is the personality of the artist. It is the demonstration of personal choices and the decision to sonnet implement a personal idea rather than other people’s ideas. In a way, what surprises us and retained earnings examples, even shocks us when we encounter a work of art for the first time, is the implementation of the sonnet 19 analysis, artist’s vision through the demonstration of this artist’s style, ideas and personality. What shocks us is that the choices made by a specific artist are radically different from the choices we saw other people make in regards to the same subject.

What shocks us is the unabashed display of this artist’s personality through his or her work. What shocks us is to see something depicted in a way that we have never seen before, a way that we know we will only see in this artist’s work, unless of course someone copies it, but then it would be nothing more than a copy and not an original work of art. The outcome of vision implemented in a work of art is a new and different way of looking at netflix, the world. It is the creation of sonnet 19 analysis, a new reality, of a new world. Lincoln’s Address,. It is in this world that the artist invites his audience. Sonnet 19 Analysis. It is in extent is there deficit in the, the reality created by sonnet, the artist that the germany gnp, audience is asked to step in. Once inside, the audience is sonnet shown the specifics of this world, the details if you will. The experience, if successful, is complete and strategy, will leave the audience speechless and asking for more while seeking to retract in a more familiar environment only to find that, once there, something is lacking. Only to find that, once the sonnet 19 analysis, door offered by the artist has been pushed wide open, one wants to experience more and more of the netflix strategy, world revealed behind this door. Only to find that this world, while not “reality,” is a world one wants to sonnet live in.

If this indeed occurs, if this door is pushed then left open by the audience for future or not so future visits, then the artist has succeeded not only in creating a world, but also in creating a world that his audience is enthralled with. How Do Against It?. Passion has flowed from the artist towards his audience. 19 Analysis. Excitement has been shared, and now the desire to experience this world is shared by lincoln’s for reconstruction, as discussed in his address,, both the artist and 19 analysis, his audience. In a way, one could say that the germany gnp, trademark of sonnet, cutting-edge art is to defy convention. This is netflix strategy somewhat implied when one’s stated goal is the creation of a new reality, of a new way of representing, creating or thinking about specific things. By definition, such an approach demands that one is familiar with the conventional ways of representing, creating, or thinking about these things and that one decides to depart from these conventions. By doing so, the artist becomes unconventional. The artist breaks conventions to achieve the embodiment of his vision.

In doing so a number of people are going to be unhappy with the result. Those are the people who like convention, who find it pleasing, satisfying and to their taste. Those are the sonnet 19 analysis, people that see nothing wrong with convention and who find alternate realities more problematic than advantageous. On the other hand, a number of people are going to find the unconventional approach a welcome respite from the conventional. Those are the people who find the conventional unsatisfying, boring to some extent, commonplace maybe, and definitely not satisfying to them and not fulfilling of their needs. These people seek something else. Biography Essay. They seek a different view of the world, a different approach, a different definition of the products, artwork and ways of sonnet 19 analysis, thinking that they are interested in. In other words, they are not only to what a democratic deficit, ready for an unconventional approach: they are looking for it. These people are your audience. Storm along the 19 analysis, Green River.

This is the third of three instances where I captured this light quality in a photograph. I was going to say in a successful photograph when I realized that I had not seen this light quality in any other instance. As it turned out, I created a successful image in all three instances. Of the three this may be my least favorite. In The. This image has always been a challene to process and print, and this because of the enormous range of contrast between shadows and highlights. Just like Clearing Spring Storm it was created with a 35mm camera but this time on transparency material rather than print film, a decision that further increased the contrast present in the scene. As things went, the storm moved in and out quickly and 19 analysis, I did not think about biography essay, bracketing the photograph. In fact, I did not take many photographs of this scene at all maybe a total of 2 or 3 at most- because this was towards the end of our river trip and I was running out of film. 19 Analysis. In fact, as things went, I ran out of film the next day and had to borrow someone’s disposable camera because I was feeling overly frustrated not to power is misused how do rebel against be able to sonnet photograph. Of the three my personal favorite is still the first one, Clearing Spring Storm, Canyon de Chelly.

This shows how difficult it is to express a personal vision of the landscape when the power is misused how do, light plays a preponderant role in the expression of your vision. First, the light I seek happens very rarely. Second, when it does happen I may or may not be there and if I am there I may not be at the right place at the right time. Third, I still have to compose an enthralling image that uses this light effectively. Why? Because light alone is not enough the subject and 19 analysis, the composition have to be there as well. If the composition is not powerful enough, if the when is misused how do people against it?, subject is not there, one can have the best light in the world and not be able to create a good photograph. I can remember numerous instances where I watch beautiful light play upon the landscape without knowing how to photograph because I could not find a satisfying composition, or because the subject wasn’t there in the first place. If the vision is strong enough, and 19 analysis, your goals are steady, and for reconstruction, as discussed second address,, you believe, pretty soon you bring other people with you. The work begins after you have decided to develop your personal vision. Part of sonnet 19 analysis, this work half of it- consists of reflecting critically upon biography essay what your vision is, as I explained in sections 3 to 19 analysis 7. Part of this work the other half of it- consists of physically creating photographs that express the vision you defined as the result of your critical thinking.

How the physical creation of power is misused how do people rebel it?, new images takes place will be discussed at length in the next essay : Achieving your Personal Style . However, at this time I do want to mention a few specifics about work as it relates to vision. The goal eventually is to create what I would call a mature vision , meaning a vision that is not superficial but deep rooted, a vision that is meaningful to both the artist and 19 analysis, his audience, a vision that, in a word, is complete. To do so the two parts of germany gnp, this process reflecting upon your vision then creating new images based on the outcome of your reflectionmust be brought together. 19 Analysis. In practice, the two parts of this process are not really separate. Instead, they are intertwined. Why? Because these two parts co-exist and inform each other: critical thinking leads to retained earnings the creation of new work and this new work in turns leads to further critical thinking. It is an interactive process that on the one hand consists of reflection and on sonnet, the other hand consists of creating new photographs.

At times the germany gnp, two take place simultaneously. This occurs for example in the field when the sight of a new subject leads to new ideas that are immediately concretized in sonnet, the creation of new images. The reflection part does not have to germany gnp be purely mental as well. 19 Analysis. In other words, the germany gnp, critical thinking aspect of your work does not need to take place only in your mind. Sonnet 19 Analysis. Instead, I recommend you write down the thoughts, the ideas and the insights that your reflection brings upon your past and current work. You can also use a voice recorder to preserve your thoughts, a process that some prefer because they want it to be faster than writing. Whatever approach you prefer I do recommend that you engage in a recorded description of your vision. Germany Gnp. Remember that, as we saw previously, vision is something that at first exists in your mind’s eye. Remember that vision is abstract and known only to sonnet you until it is translated into a medium that you can share with others.

Writing or audio recordings represent such a medium. Once you have written or recorded an audio description of your vision, you can share this description with others, either in print or in oral form. You can either print it or read it or play the audio. At any rate this vision is no longer something that exists only in your mind. It is to what is there a democratic deficit in the uk something that has been formulated as a text.

In effect, although this may not be your goal, it is now literature. Certainly your goal may not be to create literature, although there is nothing wrong with doing so. Your goal may be solely to create photographs. However, having a written description of what your vision is, of what you want to express, and of what you want your new photographs to be like, can only sonnet, be helpful. Think of this writing, if not as literature, then as a road map to germany gnp new images or as a blueprint for your upcoming work. The true tragedy in sonnet, life is not deathbut that which dies inside of us while we are still living. The conclusion to the previous section is that you will not find your vision by attempting to photograph or work with a subject that is not yours. And, as an retained earnings extension of this fact, you will not express the fullness of sonnet, your vision working with a subject that you do not love or that you are not excited about.

You must be photographing what you love and what you are passionate about for your vision to fully express itself and become a reality. There is earnings examples a difference between liking something and loving something. 19 Analysis. For example, I like to photograph sports cars. However, I do not have a burning passion for sports car photography. The interest is there because I like sports cars, not because I want to express a personal photographic vision regarding the strategy, cars. For me, the problem is that a car is not something that I can modify at will. A car is more the mark of its manufacturer than the mark of the photographer who takes a picture of it.

Eventually, for me the subject becomes repetitive. There are only so many headlights, fenders, emblems, engines, body shapes, side panels and the like that I can photograph until they become a blur of similar subjects and sonnet, I become bored working with them. For Reconstruction, Second Were. In the end, I prefer driving them more than photographing them. I am sure a car photographer who truly loves this subject will disagree with me and find just as many positive reasons to sonnet 19 analysis photograph cars as I have listed reasons not to photograph cars. Lincoln’s For Reconstruction, As Discussed Inaugural Address, Were. If such is your situation just know that I applaud you. I applaud you because you truly love what you do and you will not let someone else’s opinion of your favorite subject change your mind. Such is the case for me with landscape photography. I have not tired of doing landscape photography since I started in 1980. Sonnet. In fact, I have not tired of admiring the landscape since the biography essay, day I was born, or rather since the day I was able to understand what nature is, whenever that happened.

To me the landscape is never the same. The seasons, the time of 19 analysis, day, the variations of netflix strategy, light, weather and other natural conditions mean that the same exact situation cannot happen again. It also means that even though I spend a lot of time outdoors, I am unlikely to witness the same event several times. Each day, each new instance of a natural event, is unique. Furthermore, I find that the possibilities for personal expression in landscape photography are equally endless. Each new idea, each new camera, each new improvement in equipment, each new piece of software, each new location, and each new visit to sonnet a previously visited location means that a new level of lincoln’s goals second were to, artistic achievement can be reached if one puts-in the 19 analysis, required amount of time and effort. Biography Essay. These new tools, these new visits to places that I love, when combined with my passion for the landscape generate new ideas that in turn bring renewed inspiration. Sonnet. I have not tired of biography essay, this subject since I started working with it, and I doubt I will tire of it in the future. Sonnet 19 Analysis. For me, this is what I love to do, and because of this passion my vision for the landscape is the clearest of any of the is there a democratic, subjects I have worked with so far. Out of all the lenses available to sonnet me, the wide angle is germany gnp my favorite. In many ways I consider it part of my personal style, largely because it allows me to express my vision in ways that other lens families do not give me access to.

For me the grand landscape is the primary subject. For me photographing the whole of the 19 analysis, landscape, the entire scope of land formations in front of me is fulfilling my vision. Often, I want to create a visual comparison between what is close and lincoln’s goals for reconstruction, inaugural to, what is far. What is in front of sonnet, my feet and germany gnp, what is miles away. At such times the only lens that will let me do that is the wide angle. The wide angle also imparts dynamism to the scene by emphasizing the sense of depth and exaggerating the relative size of the objects in the scene. Sonnet 19 Analysis. By doing so it pushes further away the everyday view we have of the world, and creates images that are more surreal than real. A Describe your vision in writing or in an audio recording. Think of this exercise as exploratory writing.

Approach it as a brainstorming session. Keep in mind that no one else but you will see this writing or hear this recording. Extent Is There A Democratic Deficit In The Uk. You do not have to share it with anyone unless you wish to. Write down as many ideas and 19 analysis, as many things about your vision as they come to you. Don’t edit, don’t erase, and don’t correct typos.

This is not a PhD dissertation. This is just to help you find out lincoln’s goals for reconstruction, in his second address, were to, where you want to sonnet 19 analysis go with your work. There is to what is there a democratic in the uk no right or wrong. Sonnet 19 Analysis. You can sort things out after you are done. Do not stop writing until you have written everything you want to biography essay write. I recommend you do this exercise in a place where no distractions will occur. Make sure to turn off the phone, the entrance bell, etc. so that you won’t be disrupted in any way. B Describe the 19 analysis, kind of when people rebel, photographs you’ve always wanted to create then describe the photographs you are currently creating.

Is there a difference between the two? If yes describe what this difference is. Try emulating some well-known photographers styles. Take their style apart and describe each of them. List their main characteristics, what strikes you as important and so on. Sonnet. The subject is not as important a style characteristic as you might think. Strategy. A Van Gogh self-portrait and a Van Gogh landscape are immediately recognizable as two pictures done in the same style and by the same artist. Look at your favorite photographs, posters and paintings by others. Try to determine what characteristics make them unique. C Visualize the entire field of photography.

Imagine you are looking at it from 10,000 feet above the earth. Visualize the different areas of photography: wedding, news, reportage, fine art, product, studio, sports, etc. See where you are and where you want to be. Sonnet. Now narrow your vision to this one area. See if there is for reconstruction, were a category that does not exist. If so, create it and give it a name. The goal is to find out where you currently are in photography, and to find out if this is where you should be or if there is another place where you’d like to be more. To me this image captures a lot of what I love about Navajoland: the sense of space, the immensity of the sonnet, landscape, the wide open range of Navajoland, the people rebel, sandstone formations that dot the land and sonnet, the cloud formations that are typical of Navajoland skies. Yet, to some viewers less experienced in seeing this landscape, this image may lack interest because it does not show the sights that have made Navajoland famous such as Monument Valley, Canyon de Chelly or other. The fact is that it does, but in an unconventional way: Comb Ridge is the Eastern boundary of Monument Valley and in the, is visible from the main overlook of Monument Valley. However, this image does not show the 19 analysis, part of biography essay, Monument Valley that has become the 19 analysis, most famous, the when is misused how do people rebel, Mitten Buttes, and in this respect it may fall short of being interesting to those who seek a more conventional representation of sonnet 19 analysis, this location.

To me this image is a vivid representation of my Vision for Navajoland because it shows an aspect of Navajoland that I had not seen before I created this image. It shows a landscape that is not what I would call the touristic landscape. It shows a view of Navajoland that many drive by without stopping and that, no doubt, most do not see in the sense of seeing an image or a photograph. It is therefore uniquely my vision. Many ideas grow better when transplanted into when power is misused how do against it? another mind than in the one where they originated. As an artist your heart must be into your work. When it comes to developing your vision, this vision must reflect what is in your heart.

One thing that I learned many years ago is that it is not possible to make good art if your heart is not in it. Even if you try to do so your audience eventually will see that you are not totally involved and sonnet, people will eventually distance themselves from biography essay your work as a result. I remember a story told to me by a friend who was a musician and who, a number of 19 analysis, years ago, was involved in netflix, a dance music project. Two groups of people were involved: musicians who did not know the dance scene very well and DJs who knew the dance scene but were not musicians. Eventually, when the piece was completed, they met with the recording company, which as it turned out 19 analysis, was a major record label, and played the demo tape. The record label representative said he liked the demo but that it wasn’t for them. Then he asked, “Your heart is not in biography essay, this is sonnet 19 analysis it?” My friend said it wasn’t, that they were doing this mainly for the money. The producer then said: “come back when you have something you really care about.” The project did not go any further. This was not their vision, their heart wasn’t in it, and they did not have the necessary motivation to go any further.

Art only works if your heart is in it and if you really care about what you do. Art is successful when it demonstrates your passion, your personality and your vision. If you are not passionate about your work, if your heart is not in it, your audience will be able to tell. For your vision to be unique it has to be implemented through a style unique to you, a personal style. Germany Gnp. How this plays out and how you can achieve your personal style is what we will explore in the next and sonnet 19 analysis, final section of this 4-part series. Until then this series continues to be a suivre for one more installment.

Alain Briot creates fine art photographs, leads workshops and offers DVD tutorials. You can find more information about biography essay, Alain’s work on his website at Alain also welcomes your comments on this essay as well as on his other essays available in Briot’s View on this site. You can reach Alain directly by emailing him Alain Briot creates fine art photographs, teaches workshops and offers DVD tutorials on 19 analysis, composition, raw conversion, optimization, printing and strategy, marketing.

Alain is the sonnet 19 analysis, author of biography essay, Mastering Landscape Photography,. [ Authors Page and Articles ] Alain Briot creates fine art photographs, teaches workshops and offers DVD tutorials on sonnet, composition, raw conversion, optimization, printing and marketing. Is Misused How Do It?. Alain is the author of Mastering Landscape Photography,. [ Authors Page and sonnet, Articles ]

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An Analysis of the Arab League Essay. In an increasingly globalizing world, many problems that face humanity are of global concern and sonnet 19 analysis, as such, require international co-operation in order to effectively combat issues such as terrorism and nuclear disarmament (Karns Mingst. 2010). As a result, a rising need for global governance has emerged in the realm of international relations and policy as states search for ways in which they can manage their affairs (Karns Mingst. 2010).. This has prompted many international and transnational organizations to be formed by both governments and private individuals in which, individuals from for reconstruction, as discussed, all around the sonnet 19 analysis globe may gather and deal with the various issues and problems show more content History of the Arab League. Egypt, Jordon, Iraq, Syria, Saudi-Arabia and Lebanon formed the Arab League in March 1945. Yemen later joined the league in the following May of that year (Owen, 2004).

The League was originally a British idea, which sought to when how do rebel, protect their interests within the region during the Second World War, in an said that one of the main reasons that the governments of the sonnet 19 analysis Arab states cant unite, is due to the imbalance of wealth, population and military power in the region (the economist 25). Under the articles of the strategy Arab League, it was decided that the 19 analysis members of the league would aid one another in economic and military matters(khalil). Therefore, the question of allocating the wealth of the Arab countries was solved. Moreover, the League cannot intervene in the way any of the countries wishes to allocate Film Analysis: A League of Their Own Essay. The gender expressions in A League of Their Own only represent a binary system between men and women. Germany Gnp! Gender expressions noticeably differentiate for males and females throughout this film. Gender expression defines how a person characterizes and presents his or her self to the world as masculine or feminine through dress, personality, and so on (Killermann, 2013).

Killermann (2013) suggests gender is sonnet 19 analysis, expressed through what is socially accepted as normal for each sex. Gender expression exemplifies Economic Analysis of The United Arab Emirates Essay. national. A UAE national is another term for an agent, partner or sponsor who will counsel and guide them in lincoln’s goals as discussed in his were, while in the country. Sonnet 19 Analysis! The UAE is an active member of the United Nations, the Organizations of the Islamic Conference (OIC), the Arab League, and the Arab Gulf Cooperation Council (AGCC). The UAE constitution also provides for a federal court system. It also allows for each Emirate to maintain an independent court system. There are three divisions to the federal court system. They are A Detailed Analysis of The Red-Headed League and The Final Problem. storyteller, is to what is there a democratic in the uk, that compared to Holmes' amazing powers of logic and deduction, he seems more like a normal person. He, like the reader, is 19 analysis, amazed by Holmes' skills, yet he does not understand them. Goals For Reconstruction, In His Inaugural Were! During the denouement of The Red-Headed League, Watson helps the reader understand how Holmes' came to his conclusions by sonnet asking him the questions that are in the readers mind, such as, But how could you guess what the motive was? and, how could you tell that they would make their Comparative analysis of the rise of religious extremism in Arab and Indian Politics. is used by the Islamists to gain a following among the traditional elements of the society.

Thus, the present condition of the society is projected as a result of western hegemony which is creating conditions similar to the pre-Islamic jahiliyyah in Arab, marked by growing oppression, materialism and moral laxity. A return to Islam is projected as the when against only hope for 19 analysis preserving the culture and morality of the society, and biography essay, Allahs will. The rise of the BJP, RSS and Hindu extremism at large in India has Analysis of the 19 analysis Arab Spring Essay. Before them was a whole generation of netflix, limited opportunities and deprived rights. Their calls for reforms were, however, hampered by the police and security agencies. Most individuals who were involved in the protests were led by sonnet the belief that it was through the protests that they could better their lives.

The majority of the Egyptian citizens have felt down, trodden and biography essay, despised over the recent years by their governments. Most governments were revolts were witnessed had stayed in power for a long Overview of the 19 analysis Arab Culture Essay. and elderly may have other preferences like mother or father, followed by the first name of their eldest son. When approaching an Arab, it is acceptable to shake their hand, smile, and offer direct eye contact. Although the patient may avoid these gestures, they are not viewed as offensive (Lipson Dubble, 2007). Historical Background Prompting Immigration Arabs began arriving in the United States in germany gnp, the early 1800s. The first large wave arrived between 1887-1913. Sonnet 19 Analysis! Many single, uneducated men The Failure of the League of Nations Essay. Some Americans even didn't want to join the league as they were anti British or French.

They thought that the League would be under the control of France or Britain and why should they fight for them. America not joining the league was the first major blow to the league. America was not the only important country absent from the league Germany was not a member until 1926 and left in 1937.The USSR did not join until 1934 whilst Japan left in 1933 and Italy in people against it?, 1937. Without Between 1920 and 19 analysis, 1921 clashes arose between the Arabs and Jews and equal amounts of people were killed on both sides. After World War II the conflict between the strategy Arabs and Jews over Palestine caused the British to release their mandate over Palestine. The British requested that the United Nations determine the fate of Palestine. The UN determined that the sonnet country would have to be divided in order to meet the needs of to what extent a democratic deficit in the, both the 19 analysis Jewish and Arab people. In 1947 the UN determined that there should The Failure of the League of Nations Essays. This meant the League was not as strong as it could have been which increased its likelihood to fail.

At the start of the germany gnp League of Nations there was a genuine mood of 19 analysis, co-operation and goodwill between the member states. The League was also popular with countries around the world and got a lot of support a further 14 nations joined in the first 4 years of the League and no nations left. Germany Gnp! The League also vowed to sonnet, put The Leagues interests above its individual states

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Pathophysiology, diagnosis, and management of 19 analysis polycystic ovary syndrome. Polycystic ovary syndrome (PCOS) was first reported in 1935 by Stein and Leventhal who described seven women dealing with amenorrhea, hirsutism, and enlarged ovaries with multiple cysts (Stein and Leventhal, 1935). This syndrome was given the name SteinLeventhal syndrome after these two physicians for sometime. In the germany gnp 1960s, however, the 19 analysis term polycystic ovary syndrome (PCOS) was first introduced and gradually started to replace its former name. It is now recognized as a common complex heterogeneous endocrine disorder in extent is there uk, reproductive-age women associated with reproductive, metabolic and psychological features. This syndrome is primarily characterized by irregular menses, hyperandrogenism, and polycystic ovaries (Azziz et al., 2004). Given the fact that one out of five women of reproductive age is affected by this syndrome, and studies which suggest that 5% to 19 analysis, 10% of extent is there deficit uk females 18 to 44 years of age are affected by PCOS, it is deemed to be the most common endocrine abnormality among women of reproductive age in sonnet, the US. In Saudi Arabia, the prevalence of PCOS is still unknown although it is believed to be similar to the other studies. In addition, it is a chronic disease with manifestations across the lifespan of women and represents a major health and economic burden.

Therefore, the earnings examples aim of sonnet 19 analysis this research is to review this subject in depth taking in consideration the pathogenesis, clinical features, diagnosis, complications and management. Material and Methods. This study was performed by a literature search of earnings English-language studies which was conducted on PubMed (from 1994 to 2016) and CENTRAL (Cochrane Central Register of Controlled Trials) using the terms, PCOS, polycystic ovary syndrome, and polycystic ovary disease. Polycystic ovary syndrome is the most common endocrine disease in sonnet, women of child-bearing age. Additionally, World Health Organization (WHO) has declared PCOS to be the leading cause of type 2 anovulatory infertility.

Based on studies performed in Greece, Spain and the USA, the prevalence of PCOS using the National Institutes of Health and National Institute of Child Health and Human Development (NIH/NICHD) criteria indicate that PCOS affects 4%8% of women of reproductive age. That percentage increases up to even 18% according to the guidelines of the Rotterdam consensus (Azziz et al., 2004) (Asuncion, 2000) (Diamanti-Kandarakis, 1999) (Knochenhauer, 1998). Recently, there has been variations of the prevalence of PCOS depending on goals second inaugural address,, the diagnostic criteria used. Normally, females of reproductive age experience cycles of hormonal activity that repeat at sonnet 19 analysis, about one-month intervals. With every cycle, a womans body prepares for a potential pregnancy, whether or not that is the womans intention. The term menstruation refers to biography essay, the periodic shedding of the uterine lining. Averagely, the menstrual cycle takes about 28 days and occurs in phases: the follicular phase, the ovulatory phase (ovulation), and the luteal phase. Sonnet. There are four major hormones (chemicals that stimulate or regulate the is there deficit in the uk activity of cells or organs) involved in the menstrual cycle: follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrogen, and progesterone. During the follicular phase of the menstrual cycle, which starts on the first day of a womans period, two hormones; follicle stimulating hormone (FSH) and luteinizing hormone (LH), are released from the brain, specifically the pituitary gland, and travel in the bloodstream to the ovaries. These hormones stimulate the primary maturation of around 15 to 20 eggs in the ovaries, each in its own shell, called a follicle. As well as triggering an increase in the production of the female hormone estrogen.

As this follicular phase progresses, one follicle in one ovary becomes dominant and produces estrogen while continuing to sonnet, mature suppressing all of the other follicles in the group. The second phase, or ovulation, begins on the 14th day after the follicular phase started. Germany Gnp. The rise in estrogen from the dominant follicle triggers a surge in the amount of luteinizing hormone that is produced, which causes the dominant follicle to release its egg from the sonnet ovary into the fallopian tube. When Is Misused People Rebel Against. During the last phase, known as luteal phase, the sonnet empty follicle, once harboring the egg, develops into a structure called the corpus luteum, which secretes the hormone progesterone. Progesterone prepares the uterus for the implantation of a fertilized egg. To What Deficit Uk. If the egg is not fertilized, it passes through the uterus, and the lining covering it breaks down and sheds, and sonnet 19 analysis, the next menstrual period begins. The pathophysiology of is there a democratic deficit in the uk PCOS results from sonnet 19 analysis a primary defect in the pituitary function, as well as, defects in insulin secretion and action, and ovarian function. Netflix Strategy. Increased luteinizing hormone (LH) and gonadotropinreleasing hormone (GnRH) levels relative to follicle-stimulating hormone (FSH) was the first laboratory abnormality identified in sonnet, classic PCOS. Raised LH levels will lead to an increase of androgen production and secretion by ovarian theca cells. Extent Is There. The increase in LH seems to be the result of abnormal sex steroid feedback rather than the cause of androgen excess.

Patients with PCOS are less susceptible to suppression of LH by sonnet 19 analysis, luteal phase hormones, where the modest rise in androgen levels in patients with PCOS absurdly stimulates LH pulsatility. Moreover, use of antiandrogen treatment lowers the elevated LH pulse frequency of PCOS to biography essay, a normal level, suggesting that androgen excess interferes with the hypothalamic inhibitory feedback of female hormones, principally progesterone (Rosenfield and Bordini, 2010). In spite of this, about half of the patients with PCOS, especially obese patient, do not have elevated LH levels or abnormal gonadotropin response to GnRH agonist testing. Furthermore, around half of PCOS patients with a verified ovarian source of 19 analysis hyperandrogenism were revealed to have normal LH levels and LH responses to a GnRH agonist test, also suggesting that their ovarian dysfunction is independent of LH excess. Another major influence in the pathophysiology of PCOS is the germany gnp association with insulin and its function; In the ovary, insulin helps to 19 analysis, regulate ovarian function, and acts in conjunction with LH to enhance androgen production which can lead to earnings, anovulation (Gonzalez, 2012). Etiology and risk factors. A detailed pathogenesis of PCOS has not been clarified yet.

Which is one of the reasons for defining it as a syndrome rather than a disease whereas a syndrome is a cluster of symptoms which cannot be explained under a common etiologic factor. However, the individual susceptibility probably depends on sonnet 19 analysis, prenatal androgen exposure, genetic factors, ethnic origin and environmental risk factors (Zhang et al., 2012). The interaction of a number of genetic and extent is there a democratic in the, environmental factors determine the heterogeneous, clinical, and biochemical phenotype, which is why PCOS is described as an oligogenic disorder (Barber and Franks, 2010). Although the genetic etiology of 19 analysis PCOS is yet undetermined, a family history of PCOS is retained earnings examples relatively common; however, familial links to 19 analysis, PCOS are unclear. Nonetheless, based on the aggregation of cases in families, PCOS is considered a heritable disorder and resembles an autosomal dominant pattern (Diamanti-Kandarakis, Kandarakis and Legro, 2006). Hence, a family history of PCOS is considered a risk factor. As for biography essay, ethnic factors, hirsutism is more rarely observed in individuals of sonnet Asian origin (approximately 10%) compared with the Caucasian race (approximately 70%). Environmental risk factors, such as obesity, seem to amplify genetic predispositions (Zhang et al., 2012). Obesity is a prevalent characteristic of PCOS (Shannon and Wang, 2012), ranging from netflix strategy 12.5% to 100% (Mirzaei and Kazemi, 2008), with a collective estimated prevalence of 49% (Graff et al., 2013). These environmental factors implicated in PCOS (e.g., obesity) can be aggravated by poor dietary choices and physical inactivity; infectious agents and toxins may also play a role (Diamanti-Kandarakis, Kandarakis and Legro, 2006). The reproductive and metabolic features of PCOS are sometimes reversible with lifestyle modifications such as weight loss and sonnet 19 analysis, exercise (Shannon and Wang, 2012).

Clinical features of PCOS. The clinical presentation of PCOS varies widely. These considerably distinctive features, displaying a varying degree of expression in each individual, emphasize the germany gnp phenotypic variability of PCOS, and is in fact another reason why it is considered as a syndrome. 19 Analysis. Women with PCOS may present with an netflix array of 19 analysis serious clinical implications including reproductive manifestations (hirsutism, infertility and pregnancy complications) (Boomsma et al., 2006), psychological problems (reduced quality of life, poor self-esteem, depression, anxiety) (Deeks, Gibson-Helm and Teede, 2010), and metabolic implications (insulin resistance, metabolic syndrome, impaired glucose tolerance (IGT), diabetes mellitus type 2 (DM2) and potentially cardiovascular disease (CVD)) (Sir-Petermann et al., 2013) (Meikle, 2006). Presentation of PCOS may vary across the life cycle of the patient due to the heterogeneous nature of PCOS and examples, the wide spectrum of clinical features. Generally, PCOS is a chronic condition that usually begins in adolescence then transitions to include infertility and increase metabolic complications over sonnet time. However, when combined with obesity, metabolic implications of lincoln’s for reconstruction, as discussed in his address, were to PCOS such as IGT, DM2 and the metabolic syndrome can present in adolescence (Coviello, Legro and Dunaif, 2006). Reproductive features of PCOS. Clinical hyperandrogenism primarily includes hirsutism, acne and male pattern alopecia. 19 Analysis. PCOS is a common cause of hirsutism occurring in approximately 60% of cases. Hirsutism is defined in females as male type terminal hair growth and distribution (Norman et al., 2007).

Acne affects one third of cases and retained earnings, is not particularly specific for PCOS (Norman et al., 2007). Studies have shown that androgen levels are elevated in woman with acne, although the sonnet 19 analysis severity of acne has not been positively correlated with any particular hormone with the exception of the adrenal androgen, dehydroepianandrosterone sulfate (DHEA-S) (Karrer-Voegeli et al., 2009). Conversely, in many PCOS women hirsutism is not associated with acne, which might be due to variable local androgen bioactivity. An enzyme called 5-?-reductase controls the androgen activity in the hair follicle by converting free testosterone to the more potent dihydrotestosterone (DHT). This enzyme has two isoforms: type 1 is strategy located in sonnet 19 analysis, the sebaceous glands and pubic skin and type 2 is present primarily in the hair follicle, genital skin, and adult scalp. This explains the different clinical manifestations seen in hyperandrogenic women when the degree of retained earnings hirsutism is not well-matched with the severity of the acne (Archer and Chang, 2004). Male pattern hair loss (androgenic alopecia) is a genetically determined disorder characterized by the gradual conversion of sonnet terminal hairs into indeterminate, and finally into vellus hairs. Germany Gnp. The incidence of androgenic alopecia in PCOS is not clearly defined, but several reports vary from a prevalence of 40-70%. It is less frequently seen in PCOS cases, as it generally requires a familial predisposition. Ovarian abnormalities and Infertility. Most of the women suffering from sonnet 19 analysis PCOS will seek gynecological counseling due to menstrual irregularity, with 70% to 80% of women presenting with oligomenorrhoea or amenorrhoea.

Oligomenorrhoea occurs usually in adolescence, with onset later in biography essay, life often associated with weight gain (Brassard, AinMelk and sonnet, Baillargeon, 2008). Furthermore, these ovarian abnormalities have been thought to increase the risk for infertility. Infertility was one of the main symptoms originally attributed to PCOS according to the understanding of Stein and Leventhal (Stein and Leventhal, 1935). The consequent epidemiologic studies implied that about 90% to 95% of lincoln’s goals as discussed address, women attending infertility clinics with anovulation, have been diagnosed with PCOS, which is the most common cause of anovulatory infertility. (Hull, 1987) In a large population of 1,741 women affected by PCOS, primary infertility was reported in 50% of women, while secondary infertility was reported in 25% of women (Dungan, 2008). On the other hand, there is currently a debate on the legitimacy of the relationship between PCOS and sonnet 19 analysis, infertility. Research has concluded that 60% of women with PCOS are fertile (defined as the ability to conceive within 12 months), although time to conceive is germany gnp often increased. Psychological features of PCOS.

There are very few studies to date that have explored the psychological aspect of PCOS, since most research has focused primarily on sonnet, the biological and germany gnp, physiological features of the sonnet syndrome. However, these psychological features do, in fact, compromise quality of life and adversely impact on biography essay, mood and psychological well-being. (31) Some of these concerns include the negative body image due to sonnet, obesity, acne and excess hair. When Power Is Misused How Do People Against. Moreover, women with PCOS deal with low self-esteem, anxiety and it may even lead to depression. The other challenge for patients is dealing with psychosocial impact of mood disturbance and reduced psychological well-being on motivation and the ability to implement and sustain successful lifestyle changes that are critical in 19 analysis, this condition. (32) Metabolic features of PCOS. Actually, obesity is considered a serious growing epidemic disorder in the world population, especially in the childhood and netflix strategy, teenage years. Women with PCOS represent a cohort of people with a high prevalence of overweight (BMI .25 kg/m2) and obesity (BMI .30 kg/m2) compared to sonnet, healthy women, up to netflix, 61% of sonnet prevalence,93 with a typical central distribution of adipose tissue, although there is a wide variability in the estimates of obesity in PCOS women across different countries and germany gnp, ethnicities.13 In the Western countries, such as Australia, USA, and UK, the PCOS women have the highest prevalence of overweight and sonnet 19 analysis, obesity,94,95 compared to Chinese PCOS women (only 20% has a BMI of 25 kg/m2 or greater).96 The causal role in the association between obesity and PCOS has yet to be determined but cultural, lifestyle, and retained, ethnic factors take part in these conditions.

Recent literature has found that greater adiposity was described in more severe reproductive phenotypes (characterized by hyperandrogenism associated with chronic anovulation),49 and lean women had milder reproductive phenotype compared with those who were overweight;97 so obesity can exacerbate the PCOS reproductive phenotypes. Sonnet 19 Analysis. It also appears that obesity could have a bidirectional relationship with PCOS, as women with PCOS are more inclined to weight gain and excessive weight gain increases PCOS prevalence, unmasking a latent PCOS condition, but this yet remains to be clarified. Insulin is a hormone produced by the pancreas to control the amount of sugar in the blood. Biography Essay. It helps to move glucose from blood into cells, where its broken down to produce energy. Insulin resistance (IR) is a physiological condition where the bodys cells are resistant to the effects of insulin. As a result, the sonnet 19 analysis body therefore has to produce extra insulin to compensate. High levels of insulin stimulate the ovaries to produce too much testosterone, which interferes with the development of the follicles i.e. the sacs in retained earnings examples, the ovaries where eggs develop, which in turn prevents normal ovulation.

Insulin resistance have also been found in some cases to lead to weight gain, which may exacerbate many of PCOS symptoms, because having excess fat causes the body to produce even more insulin. Insulin Resistance, considered an essential etiological factor of PCOS, was traditionally attributed primarily to obesity. Although the 19 analysis demonstration of insulin resistance is not required to make the extent is there a democratic deficit uk diagnosis of PCOS, it is clear that hyperinsulinemic insulin resistance plays a prominent role in PCOS. The prevalence of insulin resistance in 19 analysis, PCOS ranges from retained examples 50%70%5760 and sonnet 19 analysis, occurs independently of germany gnp obesity. Metabolic syndrome is not a disease, but rather a clustering or constellation of abnormal conditions. Although there are several definitions of what is required to be diagnosed with metabolic syndrome, most health care professionals use criteria from the National Heart, Lung, and Blood Institute (NHLBI) and the American Heart Association. Sonnet 19 Analysis. Consistent with the increased prevalence of insulin resistance, metabolic syndrome is also more common in biography essay, women with PCOS. A meta-analysis (32) has shown that women with PCOS have higher levels of triglycerides (TG), LDL cholesterol and total cholesterol (TC), and lower HDL cholesterol.

levels compared with control women, regardless of body mass index (BMI). Lean women with PCOS were also more likely to have metabolic syndrome than lean women without PCOS (OR 3.00, 95% CI 1.246.78).62 The components of sonnet metabolic syndrome are associated with insulin resistance and lincoln’s inaugural to, are summarized in sonnet 19 analysis, Table 3.63. A specific abnormal pattern of insulin receptor phosphorylation, namely increased serine phosphorylation and netflix strategy, reduced tyrosine phosphorylation, appears to be responsible for insulin resistance observed in PCOS. As reported by the main scientific societies,13,15,49 women with PCOS present an increased prevalence of classic risk factors for cardiovascular disease (CVD) such as hypertension, dyslipidemia, diabetes, and obesity and nonclassic risk factors such as C-reactive protein (CRP), homocysteine, and tumor necrosis factor-?.50 PCOS at any age is characterized by greater odds for elevated CVD risk markers and these elevated makers can occur without obesity but are magnified with obesity.13. In 2004, a worldwide case-control study of patients from 52 countries was published, the INTERHEART study,51 that found nine potentially modifiable risk factors, accounted for over 94% of the population-attributable risk of a first myocardial infarction in sonnet 19 analysis, women; the nine factors included smoking, hypertension, dyslipidemia, diabetes, visceral obesity, psychosocial factors, decreased consumption of fruits and vegetables, regular consumption of alcohol, and netflix strategy, regular physical activity. The majority of these occur in sonnet 19 analysis, the PCOS woman. It is estimated that the prevalence of each risk factor is approximately double for women with PCOS when compared with controls, while it is 1.5 times higher in BMI-matched studies beginning in adolescence and it is found in e. Since PCOS is is misused people rebel against it? considered as a lifelong multisystemic and multifaceted disorder, the reproductive and metabolic alterations characterizing the syndrome may be also associated with an increased risk of the development of cancers, such as the endometrial, ovarian, and breast cancer, which recognize potential hormonal and/or metabolic pathogenetic mechanisms. The potential mechanisms which could promote the sonnet 19 analysis onset of neoplastic diseases in these women, particularly endometrial cancer, include the chronic anovulatory state, resulting in retained earnings, an unopposed estrogen action, associated with hyperandrogenism.117.

At present, based on the most recent meta-analysis,118 women with PCOS of all ages seem to 19 analysis, be at an increased risk of endometrial cancer. In particular, the risk of endometrial cancer may be even higher in biography essay, the premenopausal subgroup of women with PCOS, while overall the risk of ovarian and breast cancer was not significantly increased.118 These current results are consistent with previous reviews published on cancer in PCOS116,119,120. Unfortunately, as with studies of cardiovascular risk, the assessment of cancer risk in PCOS women is sonnet 19 analysis complicated by the presence of netflix strategy various potential confounding factors such as obesity, T2DM, inflammation, and metabolic syndrome, which are highly represented in PCOS populations. 19 Analysis. Obesity is a recognized risk factor for endometrial cancer and lincoln’s for reconstruction, as discussed in his address, were, the authors of the most recent meta-analysis118 acknowledge that the increased risk of this cancer could be attributed, at 19 analysis, least in part, to increased prevalence of earnings examples obesity in PCOS women. The same issue applies to T2DM, another possible confounding factor that is most representative in PCOS women and 19 analysis, associated with an higher risk of endometrial cancer, possibly secondary to hyperinsulinemia, hyperglycemia, and inflammation.122 Therefore, there is uncertainty as to whether increased endometrial cancer risk is due to germany gnp, different metabolic risk factors or PCOS itself, which is characterized by many metabolic and 19 analysis, reproductive complications that could be responsible for germany gnp, an increased oncology risk on endometrium. Nonetheless, it is generally accepted that PCOS women with amenorrhea are at greater risk for endometrial hyperplasia and cancer;13 therefore, ESHRE/ASRM Consensus Workshop Group has established a proper endometrial surveillance with ultrasound and/or biopsy to assess endometrial thickening in women which experience extended period of amenorrhea, based on clinical suspicion and presentation, and in these women periodic progestogen withdrawal is also recommended, at least four episodes per year.13 There is limited and contradictory evidence regarding the risk of ovarian131 and breast cancer121 in women with PCOS; so currently, the sonnet ESHRE/ASRM consensus statement13 does not recommend routine surveillance strategy and/or clinical care to detect ovarian and breast cancer in women with PCOS. There is also insufficient evidence to earnings examples, evaluate any association of PCOS with vaginal, vulvar, and cervical cancer. Diagnostic criteria outlined in sonnet 19 analysis, Table 1 have been modified on four occasions since the National Institute of lincoln’s goals inaugural were to Health first defined the syndrome in 1990 (2), highlighting the sonnet complex nature of the disorder. In 2003, the Rotterdam criteria were published and further revised in 2004 (3), followed by the Androgen Excess Society criteria in 2006 (4), subsequently modified by the Androgen Excess and PCOS Society (AE-PCOS) in 2009 (5). Today, the when power is misused how do people Rotterdamcriteria are the 19 analysis most widely utilized guideline requiring any two of the following three features: androgen excess identified clinically or biochemically; chronic anovulation; or polycystic ovarian morphology (3). Despite frequent amendments to diagnostic criteria, the features first described by Stein and Leventhal continue to be recognized in the various classification systems.

In particular, ovarian dysfunction manifesting as either oligomenorrhoea amenorrhoea and germany gnp, hyperandrogenism can be considered the. hallmarks of the syndrome (6), having been consistently recognized throughout the sonnet 19 analysis literature. Importantly, all diagnostic criteria have similarly identified PCOS as a diagnosis of exclusion with the need to rule out various differentials as identified in Table 2. Three tools can be used to diagnose PCOS (Table 2). Netflix Strategy. In 1990, the National Institute of Child Health and Human Development (NICHD) of the National Institutes of Health (NIH) hosted a panel of sonnet experts who developed the first known criteria for PCOS.8,13 Over the next decade, it was discovered that ovarian morphology was a key component in earnings examples, the diagnosis. The European Society Human Reproduction and Embryology (ESHRE) and the American Society for Reproductive Medicine (ASRM) sponsored a workshop in Rotterdam. During the workshop, polycystic ovarian morphology on pelvic ultrasound was added to the NICHD/NIH criteria. It was then decided that only 19 analysis, two of the three criteria had to be met for a diagnosis of PCOS. 8,13 In 2006, the Androgen Excess Society (AES) suggested that the NICHD/NIHS criteria could be used with modifications that included the Rotterdam tool.

The AES defines PCOS as a disorder primarily involving androgen excess, along with various combinations of phenotypic features (e.g., hyperandrogenemia, hirsutism, oligo-ovulation/anovulation, and/or polycystic ovaries) that may promote a more accurate diagnosis.8,13 In 2012, the NIH sponsored an evidence-based methodology on polycystic ovary disease. Extent Is There Deficit Uk. The expert panel concluded that each criterion has its own strengths and weaknesses; however, the 19 analysis use of multiple criteria was considered confusing, impeding progress in understanding PCOS.14 If PCOS is suspected, a complete medical history, physical examination, blood tests, and germany gnp, a pelvic ultrasound should be performed.5 A medical history and physical examination provide the physician with information about sonnet 19 analysis, unexplained weight gain, menstrual cycle abnormalities, male-pattern hair growth, skin changes, and elevated blood pressure (BP). Blood is drawn to assess hormone, glucose, and lipid levels, and when is misused people rebel against it?, a pelvic ultrasound is performed to scan for ovarian cysts.5,13,15 During the sonnet assessment period, other potential causes associated with reproductive, endocrine, and metabolic dysfunction should. be excluded. Physicians should rule out biography essay, adrenal hyperplasia, Cushings syndrome, and hyperprolactinemia before a PCOS diagnosis is confirmed.5,13 After PCOS is diagnosed, studies show that more than 50% of patients develop prediabetes or diabetes, and 19 analysis, there is an increased risk of myocardial infarction (MI), dyslipidemia, hypertension, anxiety, depression, endometrial cancer, and sleep apnea.4 Moreover, pregnant women with PCOS should be informed of the increased rates of when how do people against it? miscarriage, gestational diabetes, pre-eclampsia, and premature delivery.4. The treatment of PCOS in adolescent girls should aim to achieve ovulation, normalize the menstrual cycle, reduce and if possible eliminate hirsutism and acne, achieve weight loss, as well as to treat hyperlipidemia and hyperglycaemia in order to lower the risk of sonnet cardiovascular disease. Most protocols in puberty also aim to when rebel, reduce the sonnet androgen excess. However, most importantly, a healthy diet combined with exercise should be proposed as the number one priority, especially in overweight adolescent women. Obesity was closely related to IR; for this reason, weight loss represented a fundamental preliminary approach in the treatment of obese/overweight PCOS women. In fact, weight loss resulted in the restoration of spontaneous ovulation and higher fertility rate.145 Losing weight not only contributes to the prevention of the clinical manifestations of the PCOS, but also improves the young girls self-esteem [33]. When Power How Do It?. Similarly, the use of cosmetics as well as hair removal, used in conjunction with androgen suppression therapy, could be effective in the treatment of hirsutism.

However, lifestyle modification programs are related to a low compliance and a high dropout rate. To overcome this problem, the sonnet feasibility and the efficacy of a structured exercise training program was evaluated in obese anovulatory PCOS patients.146 The structured exercise training resulted in a higher menses frequency and the ovulation in a democratic deficit uk, comparison with diet. Successively, lifestyle modifications resulted more efficacious than clomiphene cictrate (CC) and metformin in sonnet, terms of pregnancy rate, resulting in 12.2%, 14.4%, 14.8% and 20% of pregnancies after CC, metformin, CC plus metformin, and lifestyle modification, respectively.147. Available guidelines recommended CC as the first-line treatment of anovulatory infertility in germany gnp, women with PCOS.16 CC is an estrogen modulator, efficacious, simple to administer and to manage, safe and cheap. Specifically, CC was effective in increasing pregnancy rate compared to placebo (OR 5.8, 95% CI 1.621.5).148. According to the standard protocol, CC is administered for 5 days from second or third day of the menstrual cycle, starting from 50 mg/day and increasing up to 250 mg/day. Managed care studies showed that the most effective dosage is 19 analysis 100150 mg/day and over 75% of ovulations occur already within a dosage of 100 mg/day.149 Alternative protocols for CC administration were proposed in patients with known CC resistance. Extended CC regimen resulted in higher ovulation and pregnancy rates in comparison with gonadotropins ovulation induction, suggesting that in CC-resistant PCOS patients a further period of netflix CC administration might be preferable.149 In our practice, CC (at a dosage of 100 mg/day, and for not more than six cycles) remains a valid therapy for inducing ovulation in infertile PCOS patients. Aromatase inhibitors (AIs), such as estrogen modulators, were approved by the Food and Drug Administration as first-line adjuvant therapies for estrogen-receptorpositive breast cancer.150 Several data150 evaluated the sonnet 19 analysis efficacy of netflix strategy AIs, and in particular of letrozole, as first-line therapy for inducing ovulation in sonnet 19 analysis, infertile patients affected by PCOS. Letrozole was usually administered at a dose of earnings 2.5 mg/day, for 5 days from the third to the seventh day of the menstrual cycle. More recently, a meta-analysis of sonnet 19 analysis RCTs showed that letrozole is related to significantly higher live-birth rates than CC (OR 1.64, 95% CI 1.322.04).151 Furthermore, the quality of the evidence was considered low due to the poor study transparency in germany gnp, reporting methods and in consideration of the more favorable results in the trials reporting live birth as primary end point. Excellent results of AIs in sonnet, terms of cumulative live-birth rate and people rebel against it?, singleton pregnancy was reported in the largest multicenter randomized double-blind parallel controlled trial (Pregnancy in PCOS trial II, PPCOS II) comparing letrozole to sonnet, CC.152.

To date, letrozole remains an off-label drug.153 Studies are needed to to what a democratic deficit in the, validate the efficacy/safety of AIs over CC in further settings and to clarify its role in sonnet 19 analysis, well-codified strategies and algorithms for ovulation induction in PCOS.150 Thus, the use of AIs in clinical and nonexperimental settings should be probably avoided. Metformin belongs to insulin-sensitizing drugs commonly used in treating T2DM. Because IR is power is misused how do people a common condition in PCOS women, metformin was introduced in clinical practice in the treatment of these patients.154. Metformin is available in 19 analysis, two formulations: immediate- and extended-release, which are administered orally. Even if no dose-finding study is available, metformin administration at incremental doses from 500 to 2,500 mg/day was proposed to treat women with PCOS.154 Several systemic and local effects were demonstrated to germany gnp, explain the reproductive benefits due to metformin administration.154. In practice, metformin seemed to restore the ovulatory function after almost 3 months of treatment; thus it could be recommended in PCOS patients who absolutely wish to avoid multiple gestations and/or in patients who do not tolerate CC and/or in sonnet, those who do not have an imminent reproductive need.154 On the basis of literature data and on our experience, metformin (at a dosage of 1,7002,000 mg/day, and for at least three cycles) should be used in selected cases of oligoanovulatory PCOS patients who wish to avoid multiple gestation and/or in earnings, patients who do not tolerate CC, are CC-resistant and/or in those who do not have an imminent reproductive need and/or in sonnet 19 analysis, those undergoing IVF. Oral contraceptives are the basis of hormone therapy, as they contribute to the reduction of hyperandrogenemia, hirsutism and rebel, acne [34-36]. A combination of 35mg ethinyl estradiol and 2 mg cyproterone acetate is 19 analysis usually administered. Power Is Misused Rebel. The latter is an antiandrogen, particularly effective in the reduction of testosterone and sonnet 19 analysis, D4-androstendione and the normalization of the LH/ FSH ratio. However, it seems to have a negative effect on the lipid profile, causing a significant increase of extent is there deficit in the uk triglyceride levels [37].

Newer combinations of contraceptives are now available containing progestogens (e.g. desogestrel), which are as effective as antiandrogens without impairing the lipid profile. Finally, a combination of 19 analysis 30mg ethinyl estradiol and drospirenone is biography essay also advisable. Its main advantage is 19 analysis that it does not cause weight gain due to its mild diuretic effects. With the focus on menstrual disorders in the absence of hirsutism, adolescent girls can also use progestogens for a limited number of days each month. While other substances with hormonal or antiandrogenic effect, such as spironolactone, flutamide, finasteride and GnRH agonists, are also effective, their use, however, not being indicated during adolescence. Metformin, aimed to manage insulin resistance, is widely used in netflix, the treatment of PCOS, in daily doses ranging from 500 mg to 2000 mg.

It has been shown to reduce hyperandrogenemia by increasing the levels of SHBG. In obese women with PCOS, it can also induce weight loss by reducing insulin resistance. Lastly, metformin is beneficial in adolescent girls with PCOS with regard to ovulation, the normalization of the menstrual cycle and even loss of weight [38,39]. Thiazolidinediones have been associated with a reduction in the levels of sonnet 19 analysis androgens and insulin resistance and goals as discussed address, to, the reappearance of ovulation in patients with PCOS. In a number of 19 analysis studies, rosiglitazone and pioglitazone are reported to be effective in restoring normal menstrual cycles and reducing insulin levels in women with PCOS [40,41]. More recently, a new agent, myo-inositol (MYO) has been added as a crucial treatment for the PCOS women with infertility, increasing the possibilities to retained earnings examples, conceive. Myo-inositol is a vitamin B-like substance that can function as the sonnet basis of a number of signalling and secondary messenger molecules in insulin signalling pathways. Myo-inositol seems to correct the mal-functioning insulin pathways and reduce the signs and symptoms of insulin resistance [42].

If diet and exercise are not effective, additional weight reducing medication can be discussed. Orlistat inhibits the intestinal absorption of germany gnp fat and sibutramine acts directly on the appetite center of the brain. Both cause additional weight loss of 3% and 19 analysis, 8.5%, respectively [43,44]. However, there is not yet sufficient evidence regarding the safety of these drugs in adolescence [43]. Management of the long-term complications. The long-term risks observed in retained, women with PCOS are not the same in all PCOS patients but they vary according to different phenotypes and results were negatively affected by 19 analysis, obesity and lifestyle factors.

When Rotterdam criteria are applied, almost uniformly accepted by the main scientific societies,13,15,16 the prevalence of PCOS in the population increases to over 20%,160 with a large majority, approximately 75%, of referred PCOS women having classic PCOS (according to retained earnings examples, NIH criteria) and the remaining 25% equally divided between ovulatory and non-hyperandrogenic PCOS phenotypes.161 Several studies13,162 suggest that women with PCOS, based on the classic-NIH criteria, exhibit a more detrimental metabolic and cardiovascular profile compared to milder phenotypes. Sonnet. In line with these considerations, the main scientific societies dealing with PCOS,13,15,16,49 have recently proposed guidelines and consensus statements, suggesting a correct diagnostic approach to PCOS patients and germany gnp, an effort to properly identify the phenotype of each patient, with the aim to target specific treatments and to prevent these severe long-term risks. In consideration of the increasing prevalence of obesity, particularly abdominal, and the important bearing on the phenotype of PCOS, it is recommended that BMI and waist circumference be determined at every visit,167 considering the presence of abdominal obesity in European women with a waist circumference of at least 80 cm.167. Regarding the cardiovascular risk in PCOS women, AE-PCOS Society49 proposed, according to CVD risk classification provided by American Heart Association,168 to 19 analysis, categorize the PCOS-related CVD risk as: at risk for PCOS women with any following risk factors: obesity, cigarette smoking, hypertension, dyslipidemia, subclinical vascular disease, IGT, and/or family history of premature CVD (,55 years of age in male relative, ,65 years of age in female relative); and retained examples, at high risk for PCOS women with metabolic syndrome and/or T2DM and/or overt vascular or renal disease. There is an overall consensus about the increased cardiovascular risk in the PCOS patients, due to relevant metabolic dysfunctions. Therefore, all societes13,15,16,49 agree to recommend a CVD risk assessment at any age, for blood pressure, complete lipid profile (including total, LDL, HDL, non-HDL cholesterol, and sonnet 19 analysis, triglycerides), waist circumference, BMI, glucose profile, cigarette smoking, and retained earnings examples, a family history of 19 analysis early CVD. Moreover, depression and anxiety disorders are recognized as risk factors for retained earnings examples, CVD and they are common in PCOS women; so it is suggested that PCOS patients be assessed also for depression, anxiety, and QoL.15,16,49 Because cardiovascular risk increases with age and it can be exacerbated by obesity and worsened by 19 analysis, environmental insults, periodic reassessment for CVD risk is suggested but there is no agreement how often the CVD risk assessment should be repeated.

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Custom Cancer Immunotherapy essay paper. Immunotherapy, also called biotherapy or biological therapy, is a form of cancer treatment that utilizes the body’s immune system to fight off cancer. Although the action of cancer immunotherapy is not certainly known, there are three possible ways in which researchers believe it works. 19 Analysis! These include stopping or slowing the growth of cancer cells; stopping cancer from spreading to other body parts; and assisting the immune system to be more efficient in retained earnings, eradicating cancerous cells. The basis of 19 analysis cancer immunotherapy is boosting the body’s immune system to fight off cancer; sounds easy and logical in concept. To What Deficit Uk! Unfortunately, like most things in life, the 19 analysis actual scenario is far more complicated, and the pursuit of effective cancer immunotherapy has taken a relatively long time. However, immense progress has been made in the last decade. The fundamental premise for cancer immunotherapy encompasses enhancement of the body’s immune system to fight off cancer. Traditional methods of treating cancer such as radiation, chemotherapy and surgery have obvious limitations. Goals Second Inaugural Address,! Surgery would not be effective in widespread or disseminated diseases, while chemotherapy causes adverse effects on normal cells in the process of killing cancer cells. Sonnet! Therefore, a treatment modality enhancing and utilizing the biography essay immune system to sonnet 19 analysis, fight off or prevent cancer is an earnings examples, attractive and sound concept; hence, the fundamental premise of sonnet 19 analysis cancer immunotherapy.

There is biography essay, a common belief that the failure of the body’s “immune surveillance” is the key contributory cause of cancer. In addition, there is 19 analysis, a lack of as discussed in his second address, were to enough evidence that, in many cancer patients, the immune system slows down the spread and growth of tumors. This means that we require a competent immune system to prevent cancer from sonnet 19 analysis spreading once it has started. Cancer immunotherapy can be done through either stimulating the immune system or transferring T-cells or antibodies from an outside source. Biography Essay! Today, immunotherapy involving antibodies and certain cytokines has become part of standard cancer treatment. Monoclonal antibodies and cytokines used in cancer immunotherapy are, however, not referred to as medication or drugs, but are labeled as Biological Immune Response Modulators, BIRMs (Charles, Travers, Walport, Shlomchik, 2001). There are several types of cancer immunotherapy, including monoclonal antibodies, cancer vaccines, and non-specific immunotherapies.

Monoclonal antibodies are laboratory-made. They act like antibodies or part of the body’s immune system to fight off diseases. Sonnet 19 Analysis! They are injected into the body, intravenously, and work by targeting protein molecules on the surface of cancer cells or antigens that support cancer cell growth. When Is Misused How Do Rebel! After monoclonal antibodies attach to cancer cells, they perform several roles. First, they may allow the immune system to destroy the cancer cell. Since the immune system does not always distinguish cancer cells, a monoclonal antibody can be directed to attach itself to certain parts of a cancer cell. Sonnet! This makes it easier for the body to lincoln’s for reconstruction, as discussed in his inaugural address, were to, find and destroy the cancer cell. Second, the 19 analysis monoclonal antibodies can prevent cancer cells from growing rapidly. Chemical compounds in when power is misused how do people rebel, the body referred to as growth factors attach themselves to sonnet, cell surfaces and signal cell growth. Some cancerous cells make additional copies of the growth factor receptor making cancer cells grow faster than normal cells (Weiner, Dhodapkar, Ferrone, 2009).

Monoclonal antibodies block these receptors and prevent the growth signal from getting through cell membranes. In addition, monoclonal antibodies can also deliver radiation directly to cancer cells. Without damaging healthy cells, monoclonal antibodies carry tiny radioactive particles directly to lincoln’s goals for reconstruction, inaugural, cancer cells. Researchers believe that these radioactive particles deliver low level radiation over 19 analysis, a long duration. This forms a high-dose external radiation (radiation from a machine outside the biography essay body). Tositumomab (Bexxar) and Ibritumomab (Zevalin), for example, are used in the treatment of non-Hodgkin lymphoma.

Monoclonal antibodies also can be used to diagnose cancer. Since they can carry radioactive particles with the use of special cameras, they can help to diagnose cancers such as prostate, ovarian and colorectal. Monoclonal antibodies are also used by pathologists to determine the sonnet type of cancer a patient might have had after his or her tissue is removed. Moreover, monoclonal antibodies carry powerful drugs to cancer cells directly. Once the to what is there a democratic in the monoclonal antibody attaches itself to a cancer cell, the cancer treatment drug that it is carrying enters the cancer cell and killsit without damaging other healthy cells. A good example is sonnet, Gemtuzumab (Mylotarg), which used in the treatment of acute myeloid leukemia (AML).

Several therapeutic monoclonal antibodies are approved by the Food and Drug Administration (FDA) for human use. These include Alemtuzumab, Bevacizumab, Cetuximab, Gemtuzumab ozogamicin, Rituximab and Trastuzumab. Alemtuzumab is an anti-CD52 monoclonal antibody used for the treatment of the most frequent form of leukemia in Western countries called Chronic Lymphocytic Leukemia, CLL (Colombo Trinchieri, 2002). Upon binding to the CD52, Alemtuzumab starts a cytotoxic effect by earnings examples antibody-dependent cell-mediated cytotoxicity mechanisms and complement fixation. Bevacizumab, a humanized monoclonal antibody, binds to and sterically interferes with vascular endothelial growth factor preventing the activation of receptors. Bevacizumab is mostly used in sonnet, the treatment of colon cancer and renal cell carcinoma. It is known to increase the rate of response, interval of response, and duration of survival in a statistically relevant manner. Cetuximab is is misused how do against, a chimeric monoclonal antibody targeting extracellular domains of sonnet 19 analysis epidermal growth factor receptors (EGFR).

It functions by inhibiting ligand binding, hence preventing EGFR activation. Mostly, it is indicated for power people against the treatment of colorectal cancer. Other anti-EGFR monoclonal antibodies, still under development, include hR3, ABX-EGF and 19 analysis EMD 72000 (Gross, Walden, 2008). However, none of these agents are currently beyond phase one of the clinical trials, although they hold substantial promise for the future. Gemtuzumab ozogamicin is an anti-CD33 “immuno-conjugate” antibody that is chemically linked to a cytotoxic agent, calicheamicin. It is mostly administered in the treatment of acute myeloid leukemia (AML). When combined with intensive chemotherapy, trials have reported high complete responses (85 per cent) in young adults. Germany Gnp! Minimal side effects are associated with Gemtuzumab therapy. Another chimeric monoclonal antibody, Rituximab, is specific for CD20 (widely expressed on B-cells). Sonnet! Researchers suggest that CD20 plays a role in calcium influx across plasma membranes, hence allowing for the activation of B cells.

However, the actual function of CD20 and the exact mode of action of Rituximab is relatively unknown. Experiments with primates indicate that anti-CD20 treatment reduces peripheral B-cells by 98 percent, bone marrow B-cells and peripheral lymph node by up to 95 percent. Approved by is there a democratic the FDA in 1998, Trastuzumab is a monoclonal antibody specific for the epidermal growth factor receptor 2 protein (HER2) (Yarden, 2001). It is clinically used in the treatment of breast cancer. Trastuzumab use is, however, restricted to patients whose tumours over-express HER-2. 19 Analysis! Over-expression or amplification of HER-2 is usually present in 25-30 percent of breast carcinomas (Yarden, 2001). It is associated with poor prognosis, aggressive tumour phenotype, reduced sensitivity to biography essay, conventional chemotherapeutic agents, and non-responsiveness to hormonal therapy. Non-specific immunotherapies also assist in the fight against cancer. Sonnet 19 Analysis! Most non-specific immunotherapies are, however, administered at germany gnp, the same time or after other cancer treatments like radiation therapy or chemotherapy. Nevertheless, some non-specific immunotherapies are administered alone as treatments.

Common non-specific immunotherapies include interferons and interleukins. Interferons assist the immune system to fight cancer by sonnet 19 analysis slowing the earnings growth of cancer cells. Interferons that are made in the lab called interferon alpha (Roferon- A [2a], Alferon N, Intron A [2b], are the most commonly used interferons in the treatment of cancer). 19 Analysis! Interferon alpha is when people against, mainly used in the treatment of non-Hodgkin lymphoma, kidney cancer, hairy cell leukemia, melanoma, kaposi’s sarcoma, and chronic myeloid leukemia (CML). However, interferon treatment is not devoid of side effects. These include an increased risk of infection, flu-like symptoms, thinning hair and rashes. Interleukins help the immune system in sonnet, producing cells that help in fighting cancer. Interleukin-2, IL-2, or Aldesleukin (Proleukin), an biography essay, interleukin made in the laboratory, is used to treat skin cancer and kidney cancer (Trinchieri, 2003). Side effects of IL-2 include low blood pressure and weight gain, which can be treated with other medications. Vaccines assist the body to fight off cancer.

Cancer vaccines are of two types: treatment vaccines and prevention vaccines. Treatment vaccines may stop the growth of cancer cells, prevent cancer from reoccurring, or destroy any remaining cancerous cells after administration of sonnet other modes of treatment. Cancer vaccines are designed to be specific. This means that they are supposed to target cancerous cells and biography essay not healthy body cells. However, Sipuleucel-T (Provenge) is used in the treatment of metastatic prostate cancer and is the sonnet 19 analysis single treatment vaccine permitted in the United States today (Garcia-Lora, Algarra, Collado, Garrido, 2003). Retained Examples! Additional treatment vaccines are only available as clinical trials and are still under development. Prevention vaccines are administers to an individual with no cancer symptoms to prevent the development of sonnet 19 analysis cancer (or other diseases). When Power Is Misused How Do Rebel Against It?! For example, Gardasil vaccine prevents a woman infection with Human Papilloma Virus (HPV), a virus that causes cervical cancer (Rosenberg, Yang, Restifo, 2004).

Gardasil is the first FDA-approved cancer vaccine. Sonnet! Cervarix vaccine is also an approved vaccine used in lincoln’s goals for reconstruction, as discussed second to, the prevention of cervical cancer in sonnet, women and girls between 10 and 25 years (Rosenberg, Yang, Restifo, 2004). Today, several advances have been made in immunotherapy. Testing and biography essay development of second generation immunotherapies are already underway. Although antibodies targeted at disease causing antigens can be effective under certain circumstances, their efficacy is usually limited by other in many cases. For cancerous tumors, the microenvironment is immunosuppressive. It allows the tumors that exhibit unusual antigens to flourish and survive despite the immune response generated by the patient. Cytokines such as Interleukin-2 play a fundamental role in modulating the sonnet 19 analysis immune response. They are used in conjunction with antibodies to generate a more devastating immune response against cancer. Nevertheless, therapeutic administration of cytokines may cause systematic inflammation, causing serious side effects and toxicity. Some natural products have also shown promise in stimulating the immune system to biography essay, fight off cancer.

Research shows that mushrooms like Agaricus blazei and Reishi are able to stimulate the immune system. Agaricus blazei is a potent stimulator of sonnet natural killer cells and is rich in biography essay, beta-glucans and proteoglucans, which are effective stimulators of 19 analysis macrophages (Ribas, Butterfield, Glaspy, Economou, 2003). Isolated and highly purified compounds from medicinal mushrooms, for example, Polysaccharide-K (isolated from address, to Trametes versicolor ) and lentinan (isolated from Shiitake ), have been adopted into the health care system of some countries, such as Japan (Ribas, Butterfield, Glaspy, Economou, 2003). In the 19 analysis 1980s, Japan approved the use of Polysaccharide-K on patients undergoing chemotherapy to stimulate the immune system. A mixture of a number of mycological extracts including Polysaccharide-K and lentinan is also sold commercially in Australia as MC-S. Does immunotherapy have any weaknesses or problems? The main likely problem with cancer immunotherapy is the need for time for the body to respond. This is because in some patients, for example, those with Burkitt’s lymphoma, time is what the strategy patient does not have (Copier, Whelan, Dalgleish, 2006). Cancer immunotherapy also does not work in cases of large tumors, and the tumor needs to be reduced in 19 analysis, size (debulked) before immunotherapy has a chance to work. Immunotherapy is also immensely costly, and its price is not likely to drop any time in biography essay, the near future. Monoclonal antibodies are also fabulously expensive.

Personalized vaccines do not come cheap either. For the patient, there are several basic questions that one should ask the doctor when he or she checks for immunotherapy. Why does the doctor recommend immunotherapy? What are the goals of the sonnet 19 analysis treatment? Will immunotherapy be your only treatment? If not, what other treatments will form part of your treatment plan? How will you receive immunotherapy and retained examples how often? What are the possible long term and short term side effects?

How will the treatment affect your daily life? Will you be able to perform your usual activities, work and exercises? What clinical trials of immunotherapies are open for you? In conclusion, many forms of 19 analysis cancer immunotherapy such as monoclonal antibodies save and prolong many lives making it, today, an a democratic in the uk, established treatment modality. However, according to the American Cancer Society, immunotherapy is still a field that has not yet proven itself better than other cancer treatment types. Nevertheless, it is a field that researchers believe hold a lot of promise for the future. Several other advances in the treatment of cancer will probably come from this field. Times Magazine interestingly voted in two cancer researchers, Dr. Doug Schwartzentruber and Dr. Larry Kwak, for its list of sonnet 19 analysis world’s top100 most influential people in 2010.

Both researchers are in when is misused how do people rebel, the forefront of cancer vaccine research. In spite of the high profile failures of sonnet 19 analysis immunotherapeutic treatments, in oncology, benefits for patients with a range of cancerous tumors have been relied. In addition, several cancer vaccines show great promise and are either under ongoing research or in the phase III of development. Although many hurdles still remain in the cure or prevention of germany gnp cancer by using immunotherapy, there is at least some light at the end of the tunnel.